Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition
Atopic Dermatitis, Eczema, Atopic
Sex
Male or Female
Age
18 - 64 years
Healthy participants
No
Visit ClinicalTrials.gov for more information

Eligibility criteria

Study overview

The purpose of this study is to learn if the study medicine (PF-08049820) is safe and effective for the treatment of atopic dermatitis (AD), also known as eczema, or atopic eczema. People with this condition may have severe itching and rashes on the skin.

The study is seeking participants who:

1. Are 18 to 64 years of age;
2. Were confirmed to have AD at least 6 months ago;
3. Do not have a suitable prescribed medicine for AD;
4. Are considered by their doctors to have moderate to severe AD.

The study has two stages (Stage 1 and Stage 2). In both stages, eligible participants will take either PF-08049820 or placebo as tablets by mouth daily for 12 weeks. A placebo does not have any medicine in it but looks just like the medicine being studied. Participants will visit the clinic on Day 1, Weeks 1, 2, 4, 6, 8 and 12. They will have a follow-up visit at Week 16. During this time, the participant's health and skin condition will be checked. They will have blood and urine tests. They will also have to answer questions about their health, skin condition, and how much their skin condition affects their lives. The experiences of participants receiving the study medicine will be compared to those receiving placebo. This will help to understand if PF-08049820 is safe and effective.

View locations for this study

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    Miles
    0500

    Nearest Locations found

    49 sites found

    Apex Clinical Research Center, LLC.

    Mayfield Heights, Ohio, United States, 44124
    recruiting status
    Recruiting
    Site Info

    Apex Clinical Research Center, LLC. - Lorain

    Lorain, Ohio, United States, 44053
    recruiting status
    Recruiting
    Site Info

    CCR Ostrava, s.r.o.

    Ostrava, Czechia, 702 00
    recruiting status
    Recruiting
    Site Info

    Centre de Recherche Saint-Louis inc.

    Québec, Canada, G1W 4R4
    recruiting status
    Recruiting
    Site Info

    Centrum Badań Klinicznych Jagiellońskie Centrum Innowacji sp. z o.o.

    Krakow, Lesser Poland Voivodeship, Poland, 30-348
    recruiting status
    Recruiting
    Site Info

    Centrum Medyczne Angelius Provita

    Katowice, Poland, 40-611
    recruiting status
    Recruiting
    Site Info

    Clinical Science Institute

    Santa Monica, California, United States, 90403
    recruiting status
    Recruiting
    Site Info

    DERMAMEDICA s.r.o.

    Náchod, Czechia, 547 01
    recruiting status
    Recruiting
    Site Info

    Dermatology Research Institute

    Calgary, Alberta, Canada, T2J 7E1
    recruiting status
    Recruiting
    Site Info

    Dermatology and Ophthalmology Kume Clinic

    Sakai, Osaka, Japan, 593-8324
    recruiting status
    Recruiting
    Site Info

    Fukuwa Clinic

    Chuo-ku, Tokyo, Japan, 104-0031
    recruiting status
    Recruiting
    Site Info

    Gsi Clinical Research

    Margate, Florida, United States, 33063
    recruiting status
    Recruiting
    Site Info

    Guangdong Province Dermatology Hospital

    Guangzhou, Guangdong, China, 510091
    recruiting status
    Recruiting
    Site Info

    Hattori Dermatology Clinic

    Takasaki, Gunma, Japan, 370-0071
    recruiting status
    Recruiting
    Site Info

    Hopital Charles Nicolle

    Rouen, France, 76031
    recruiting status
    Recruiting
    Site Info

    Huashan Hospital, Fudan University

    Shanghai, Shanghai Municipality, China, 200040
    recruiting status
    Recruiting
    Site Info

    Kosugi Dermatology Clinic

    Kawasaki-shi, Kanagawa, Japan, 211-0063
    recruiting status
    Recruiting
    Site Info

    Laser Clinic S.C. dr Tomasz Kochanowski dr Andrzej Królicki

    Szczecin, West Pomeranian Voivodeship, Poland, 70-332
    recruiting status
    Recruiting
    Site Info

    Marvel Clinical Research

    Huntington Beach, California, United States, 92647
    recruiting status
    Recruiting
    Site Info

    Mayo Clinic

    Scottsdale, Arizona, United States, 85259
    recruiting status
    Recruiting
    Site Info

    Mayo Clinic Hospital

    Phoenix, Arizona, United States, 85054
    recruiting status
    Recruiting
    Site Info

    Mayo Clinic Specialty Building

    Phoenix, Arizona, United States, 85054
    recruiting status
    Recruiting
    Site Info

    Montefiore - Clinical Research Center

    The Bronx, New York, United States, 10467
    recruiting status
    Recruiting
    Site Info

    Montefiore - Greene Medical Arts Pavillion

    The Bronx, New York, United States, 10467
    recruiting status
    Recruiting
    Site Info

    Montefiore - Jacobi Dermatology Clinic

    The Bronx, New York, United States, 10461
    recruiting status
    Recruiting
    Site Info

    Montefiore - The Dermatology Center

    The Bronx, New York, United States, 10467
    recruiting status
    Recruiting
    Site Info

    Montefiore Medical Center

    The Bronx, New York, United States, 10467
    recruiting status
    Recruiting
    Site Info

    Nihonbashi Sakura Clinic

    Chuo-ku, Tokyo, Japan, 103-0025
    recruiting status
    Recruiting
    Site Info

    Northridge Clinical Trials

    Northridge, California, United States, 91325
    recruiting status
    Recruiting
    Site Info

    Paddington Testing Co, Inc

    Philadelphia, Pennsylvania, United States, 19103
    recruiting status
    Recruiting
    Site Info

    Peking University People's Hospital

    Beijing, China, 100044
    recruiting status
    Recruiting
    Site Info

    Penta Hospitals Badania Kliniczne- Gdańsk 1

    Gdansk, Poland, 80-546
    recruiting status
    Recruiting
    Site Info

    Pratia Czech s.r.o.

    Pardubice, Czechia, 530 02
    recruiting status
    Recruiting
    Site Info

    Pratia Czech s.r.o.

    Prague, Czechia, 130 00
    recruiting status
    Recruiting
    Site Info

    Queen's square Medical Facilities Queen's square Dermatology and Allergology

    Yokohama, Kanagawa, Japan, 220-6208
    recruiting status
    Recruiting
    Site Info

    The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, China, 350005
    recruiting status
    Recruiting
    Site Info

    The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, China, 350008
    recruiting status
    Recruiting
    Site Info

    Toronto Research Centre

    Toronto, Ontario, Canada, M3H 5Y8
    recruiting status
    Recruiting
    Site Info

    UPMC Department of Dermatology

    Pittsburgh, Pennsylvania, United States, 15213
    recruiting status
    Recruiting
    Site Info

    ASMC - IPSMC - skin and venereal diseases

    Sofia, Sofia (stolitsa), Bulgaria, 1407
    not yet recruiting status
    Not yet recruiting
    Site Info

    Dermedic Jacek Zdybski

    Kielce, Poland, 25-553
    not yet recruiting status
    Not yet recruiting
    Site Info

    Diagnostic Consultative Center "Ascendent"

    Sofia, Bulgaria, 1202
    not yet recruiting status
    Not yet recruiting
    Site Info

    Diagnostic Consultative Centre (DCC) - Foкus 5

    Sofia, Sofia (stolitsa), Bulgaria, 1463
    not yet recruiting status
    Not yet recruiting
    Site Info

    Hopital Larrey

    Toulouse, France, 31059
    not yet recruiting status
    Not yet recruiting
    Site Info

    Hopital Saint Louis

    Paris, France, 75010
    not yet recruiting status
    Not yet recruiting
    Site Info

    Metropolis Dermatology - DTLA

    Los Angeles, California, United States, 90017
    not yet recruiting status
    Not yet recruiting
    Site Info

    University Hospital Schleswig-Holstein

    Kiel, Germany, 24105
    not yet recruiting status
    Not yet recruiting
    Site Info

    Universitätsklinikum Münster

    Münster, North Rhine-Westphalia, Germany, 48149
    not yet recruiting status
    Not yet recruiting
    Site Info

    Universitätsklinikum Schleswig-Holstein

    Lübeck, Schleswig-Holstein, Germany, 23538
    not yet recruiting status
    Not yet recruiting
    Site Info
    • Recruitment Status
    • Site details
    • Study Contact
    • Clinical Trials ID

    Study Locations

    View locations for this studyFind the closest location, your results will be shown belowFind the closest location