Chronic and acute health conditions can significantly harm an individual’s overall health if they are not treated effectively.

We invite you to explore our clinical trials in internal medicine below.

Explore our internal medicine clinical trials

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Pfizer has clinical trials for adults and children across internal medicine conditions. Select from the list below to view clinical trials that are looking for participants.

Together, we can advance breakthroughs for all 

It is important to have medicines that can treat diseases and conditions in anyone, regardless of their background.

This starts with clinical trials. Many biological and environmental factors, such as genetics, race, ethnicity, age, sex, gender, and where you are born can impact how you may respond to a medicine. Even where and how you live, work and play can affect your health, your risk for disease, or your response to treatment.

When clinical trial participation reflects the diversity of our communities, the more we learn about potential medicines, including how they work for different people. Everyone needs to be represented.

About internal medicine

Internal medicine includes many different conditions. Some of these, such as high blood pressure, high cholesterol, or diabetes, are familiar to most of us because we have one or more of them or know someone who does. Even though safe and effective treatments are already available for many of them, we continue to learn about new, different, and potentially better options.

Areas of focus for Pfizer’s clinical research in internal medicine include cardiovascular diseases, diabetes, infectious diseases, liver disorders, and obesity.

Frequently asked questions

Why are there clinical trials for chronic conditions, such as cardiovascular diseases or diabetes, that already have treatment options?

Even though safe and effective treatments are already available for many of these conditions, we continue to learn about new, different, and potentially better ways of treating them.

The goal is to provide the best treatment options for every individual. For some people, the current treatments are not enough. We are seeking to develop new treatment options, either given alone or in combination with current treatment options, that we hope will improve outcomes for these individuals.

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Why is Pfizer conducting clinical research related to obesity?

Obesity can have significant impact on a person’s overall health.

We know that obesity increases people’s risk of high blood pressure, heart disease, diabetes, cancer, and other chronic conditions. We also know there are many reasons why it is difficult for people to manage their weight and avoid being obese.

Developing treatments for obesity may help those who struggle with their weight to potentially lower their risk of other health conditions.

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What happens in a clinical trial?

What happens in a clinical trial depends on the ‘protocol.’ A protocol is a detailed plan that explains the purpose of the clinical trial and how it will be run. If you consider joining a clinical trial, these details will be explained to you as part of the informed consent process. They include: 

  • the length of the clinical trial 
  • the study medicines, procedures, and tests in the clinical trial  
  • the schedule of study activities 
  • information about who can participate 
  • how side effects will be tracked, managed, and reported 
  • the rules that must be followed 

A clinical trial may also have aspects such as randomization, placebo, or blinding.

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Who can join a clinical trial?

We encourage everybody to consider joining clinical trials. There are many types of clinical trials that study different aspects of health in people with a variety of backgrounds and conditions. Each clinical trial has its own criteria for who may participate. These are called eligibility criteria.  
 
Eligibility criteria include things like your age, sex, overall health, type of condition, and your medical treatment history. As part of the steps to join a clinical trial, the study doctor will confirm whether you meet all eligibility criteria and are able to participate.

Participation in a clinical trial is always voluntary. The decision to join is personal, and it is yours.
 
To learn more about Pfizer’s clinical trials, visit Our Research or search for trials here. 

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Who can I contact regarding Pfizer clinical trials?

We list all of our clinical trials that are recruiting participants or plan to recruit shortly in our Find a Trial search engine. We welcome you to explore our clinical trials and the information provided about each study. There is contact information available on each study’s webpage.

For general inquiries about Pfizer clinical trials, you may call 1-800-887-7002 or email [email protected].

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What if I can’t find a clinical trial that’s right for me on this website?

Our Find a Trial search engine only provides information about Pfizer clinical trials. To search for all registered clinical trials, regardless of the study sponsor, you may visit ClinicalTrials.gov.

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      Pfizer clinical trials

      Search Results

      We found 36 clinical trials for: Internal Medicine, 150 miles

      4 trials recruiting
      Migraine Clinical Trials
      We are conducting additional research to better understand the safety and effectiveness of rimegepant for other populations, like children, teens, and adults with other types of migraines and health conditions.
      • Internal Medicine
      • Recruiting
      2 trials recruiting
      Weight Management Clinical Trials
      Our Weight Management Clinical Trials are enrolling people living with overweight, obesity, and other weight-related conditions.
      • Internal Medicine
      • Recruiting
      1 trial recruiting
      1 trial not yet recruiting
      Vesper-OSA studies
      These clinical trials are enrolling people living with obstructive sleep apnea and overweight or obesity. These clinical trials are evaluating if a monthly GLP-1 RA study medicine can help improve symptoms of sleep apnea in people living with overweight or obesity.
      • Internal Medicine
      • Recruiting
      • Not yet recruiting
      Recruiting
      A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
      • Internal Medicine
      • Recruiting
      NCT07845500
      Sex: All
      Age: 18+
      Locations: 26
      View study
      Recruiting
      A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
      • Internal Medicine
      • Recruiting
      NCT07595549
      Sex: All
      Age: 18+
      Locations: 80
      View study
      Recruiting
      A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)
      • Internal Medicine
      • Recruiting
      NCT07823608
      Sex: All
      Age: 18+
      Locations: 8
      View study
      Recruiting
      Randomized Study in Children and Adolescents With Migraine: Acute Treatment
      • Internal Medicine
      • Recruiting
      NCT04649242
      Sex: All
      Age: 6 - 17
      Locations: 246
      View study
      ...
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