Internal medicine includes many different conditions. Some of these, such as high blood pressure, high cholesterol, or diabetes, are familiar to most of us because we have one or more of them or know someone who does.

These conditions can significantly harm an individual’s overall health if they are not treated effectively. Even though safe and effective treatments are already available for many of them, we continue to learn about new, different, and potentially better options.

Areas of focus for Pfizer’s clinical research in internal medicine include cardiovascular diseases, diabetes, infectious diseases, liver disorders, and obesity. We invite you to explore our clinical trials in internal medicine below. 

Explore our clinical trials in internal medicine


Select from the list below to view Pfizer clinical trials that are looking for participants. If you do not find what you are looking for, try using the search box below.

Atrial fibrillation

Blood clots

Coronavirus (COVID-19)


Erosive esophagitis

Heart failure



Refine your search

Looking for a specific condition? Find a Pfizer clinical trial using the search box below.

To get started, enter the condition, keyword, or NCT number you want to search for. You can refine your search by selecting ‘Show filters’.

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      Get notified about Pfizer clinical trials that may be right for you — now and over time.

      Frequently asked questions

      Why are there clinical trials for chronic conditions, such as cardiovascular diseases or diabetes, that already have treatment options?

      Even though safe and effective treatments are already available for many of these conditions, we continue to learn about new, different, and potentially better ways of treating them.

      The goal is to provide the best treatment options for every individual. For some people, the current treatments are not enough. We are seeking to develop new treatment options, either given alone or in combination with current treatment options, that we hope will improve outcomes for these individuals.

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      Why is Pfizer conducting clinical research related to obesity?

      Obesity can have significant impact on a persons overall health.

      We know that obesity increases peoples risk of high blood pressure, heart disease, diabetes, cancer, and other chronic conditions. We also know there are many reasons why it is difficult for people to manage their weight and avoid being obese.

      Developing treatments for obesity may help those who struggle with their weight to potentially lower their risk of other health conditions.

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      What happens in a clinical trial?

      What happens in a clinical trial depends on the protocol. A protocol is a detailed plan that explains the purpose of the clinical trial and how it will be run. If you consider joining a clinical trial, these details will be explained to you as part of the informed consent process. They include: 

      • the length of the clinical trial 
      • the study medicines, procedures, and tests in the clinical trial  
      • the schedule of study activities 
      • information about who can participate 
      • how side effects will be tracked, managed, and reported 
      • the rules that must be followed 

      A clinical trial may also have aspects such as randomization, placebo, or blinding.

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      Who can join a clinical trial?

      We encourage everybody to consider joining clinical trials. There are many types of clinical trials that study different aspects of health in people with a variety of backgrounds and conditions. Each clinical trial has its own criteria for who may participate. These are called eligibility criteria.  
      Eligibility criteria include things like your age, sex, overall health, type of condition, and your medical treatment history. As part of the steps to join a clinical trial, the study doctor will confirm whether you meet all eligibility criteria and are able to participate.

      Participation in a clinical trial is always voluntary. The decision to join is personal, and it is yours.
      To learn more about Pfizers clinical trials, visit Our Research or search for trials here

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      Who can I contact regarding Pfizer clinical trials?

      We list all of our clinical trials that are recruiting participants or plan to recruit shortly in our Find a Trial search engine. We welcome you to explore our clinical trials and the information provided about each study. There is contact information available on each studys webpage.

      For general inquiries about Pfizer clinical trials, you may call 1-800-887-7002 or email [email protected].

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      What if I can’t find a clinical trial that’s right for me on this website?

      Our Find a Trial search engine only provides information about Pfizer clinical trials. To search for all registered clinical trials, regardless of the study sponsor, you may visit

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      Learn about NASH, a liver condition that Pfizer is studying

      Combating cardiovascular diseases

      There have been significant advances in the treatment of cardiovascular diseases in recent decades. Many patients with these conditions are living longer and with better quality of life. This is in large part due to the treatments that have been developed through clinical research. But the work continues. Learn more about Pfizer’s ongoing efforts to tackle cardiovascular diseases, the world’s leading cause of death. 

      Learn more on

      Combating cardiovascular diseases

      Cardiovascular disease patient and healthcare provider
      Cardiovascular disease patient and healthcare provider
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      Steps to join a clinical trial

      How clinical trials work

      Protecting your safety & privacy

      For caregivers