Asthma is a long-term respiratory condition that is caused by inflammation in the lungs and airways. This inflammation leads to symptoms such as shortness of breath, difficulty breathing, chest tightness, coughing and wheezing.
Asthma symptoms can vary over time and in intensity, and can be triggered by factors such as exercise, allergen exposure and changes in weather. Asthma can also be caused by an overactive immune system.
Patients with uncontrolled moderate-to-severe asthma do not respond well to standard inhaled treatments and there is a need for more effective therapies to better control the symptoms and causes of asthma.