Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition
Lyme Borreliosis
Sex
Male or Female
Age
18 - 44 years
Healthy participants
Yes

Eligibility criteria

Study overview

The purpose of this study is to learn about the safety and effects of the Lyme disease vaccine (called VLA15) when given at different time points.

This study is seeking participants who:

  • are generally healthy and between 18 and 44 years of age,
  • have never had a vaccine for Lyme disease before,
  • are not currently taking, or haven't recently taken, medicines like chemotherapy, blood products, or blood thinners, and
  • are not pregnant or breastfeeding and do not plan to become pregnant while receiving the study vaccine.


All participants in this study will receive a total of 5 doses through a shot in the upper arm. Four doses will be the study vaccine (VLA15), and 1 dose will be saltwater.

The study will compare the experiences of people receiving the study vaccine at different time points. This will help see if the study vaccine is safe and will help understand its effect on the body.

Participants will take part in this study for about 2 years. During this time, the participants will have 11 planned visits - 8 will be at the study clinic and 3 will be done over the phone. The clinic visits may include having a health check, giving a small amount of blood (about 20 mL or 4 teaspoons), and getting the study vaccine or saltwater as a shot.

View locations for this study

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    Miles
    0500

    Nearest Locations found

    5 sites found

    Preferred Primary Care Physicians

    Uniontown, Pennsylvania, United States, 15401
    recruiting status
    Recruiting
    Site Info

    Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair

    Pittsburgh, Pennsylvania, United States, 15243
    recruiting status
    Recruiting
    Site Info

    Amherst Family Practice, P.C.

    Winchester, Virginia, United States, 22601
    not yet recruiting status
    Not yet recruiting
    Site Info

    Clinical Research Partners, LLC

    Richmond, Virginia, United States, 23226
    not yet recruiting status
    Not yet recruiting
    Site Info

    Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18)

    Pittsburgh, Pennsylvania, United States, 15236
    not yet recruiting status
    Not yet recruiting
    Site Info
    • Recruitment Status
    • Site details
    • Study Contact
    • Clinical Trials ID

    Study Locations

    View locations for this studyFind the closest location, your results will be shown belowFind the closest location