For people living with overweight or obesity, managing weight is a lifelong journey. Many try changes to eating habits and physical activity, but some people need additional help to reach their weight loss goals.
We recognize how personal and complex weight management can be. That’s why we are researching new study medicines that may offer additional support when used alongside diet and exercise.
Participating in these clinical trials
We invite you to explore our clinical trials for weight management. Our goal is to learn whether the study medicines are safe and effective treatment options for people living with overweight or obesity and other weight-related conditions. With your help, we can find new and better ways to support people on their weight‑management journey.
Before you decide to participate in one of our clinical trials, the study doctor and their team will review the clinical trial details with you, including what you can expect during the clinical trial, the length of participation, and potential risks and benefits.
We're currently enrolling people with the following conditions:
Overweight and obesity
Type 2 diabetes
Urinary incontinence (UI)
Polycystic ovary syndrome (PCOS)
Obstructive sleep apnea
Hypogonadotropic hypogonadism
Knee osteoarthritis
Each clinical trial will have its own unique requirements for who may participate (eligibility criteria). To learn more about the requirements for a clinical trial that is actively recruiting, visit the clinical trial’s webpage below. Only the study staff can determine if you qualify to enroll in a clinical trial.
Weight Management Clinical Trials
Frequently asked questions
These clinical trials are being conducted to see if the study medicines may help reduce weight and the symptoms associated with certain weight-related conditions.
Each clinical trial is unique and has different requirements to determine who is eligible to participate. You can learn more about the eligibility criteria on each clinical trial’s webpage. The study team will help you decide if taking part in one of our weight management trials is right for you.
Yes, the information you provide will not be shared with anyone who is not directly associated with this clinical trial without your permission, except as required by law or as set forth in the informed consent.
Health insurance is not required to take part in these clinical trials.
The study medicine and any study-related procedures are provided at no cost. You will also be reimbursed for study-related expenses such as parking and other transportation costs (check with the study team as this may vary).
About overweight and weight-related conditions
Excess weight can affect health not just in the short term, but over time as well. Carrying extra weight places ongoing strain on multiple body systems, increasing the risk of conditions such as cardiovascular disease, high blood pressure, type 2 diabetes and other metabolic disorders, liver disease, and joint health. These effects often develop gradually, which is why weight-related conditions can progress quietly before symptoms become noticeable
Pfizer is committed to advancing scientific research aimed at better understanding weight-related conditions and discovering potential breakthroughs in weight management to help improve long-term health for people living with these conditions.
Why participate in one of our clinical trials
If one of our Weight Management Clinical Trials is a good fit for you and you decide to take part, you may receive:
- Access to study medicines and/or standard of care treatment at no cost
- Diet and exercise counseling
- Tools to help you in your weight loss journey
- Reimbursement for any reasonable expenses you may have as a result of taking part in a clinical trial such as parking and travel-related expenses
- The opportunity to help advance scientific knowledge of weight-related conditions and potentially help others with these conditions in the future
Together we can make a difference
Many factors—including age, sex, race, ethnicity, other health conditions, and lifestyle—can affect a person’s weight and how they respond to weight loss treatment. Since people respond to treatment differently, it’s important for these clinical trials to include participants from a wide range of backgrounds. This will help us better understand how the study medicines work for different people.
Your participation and commitment could make a difference for you and others who also struggle with managing their weight.
