Many of Pfizer’s phase 1 clinical trials take place at the Pfizer Clinical Research Unit (PCRU) in New Haven, Connecticut. The participants in these clinical trials commonly don’t have the disease or condition that will later be studied. That’s why the participants are called “healthy volunteers.” 

Healthy volunteers in these clinical trials help us understand how a study drug affects the body before people with the condition are included. This is one way to assess a study drug’s safety before giving it to those who have a medical condition.

Healthy volunteers truly make a difference as we strive for breakthroughs that change patients’ lives.

If you’re interested in participating, take a look at the PCRU’s ongoing clinical trials below.

A look inside our facility

Pfizer New Haven Clinical Research Unit
Pfizer New Haven Clinical Research Unit
Pfizer New Haven Clinical Research Unit
Pfizer New Haven Clinical Research Unit
Pfizer New Haven Clinical Research Unit
Pfizer New Haven Clinical Research Unit

Our clinical research unit is a modern facility that provides study-related clinical care and monitoring of the participants in our clinical trials. The New Haven Clinical Research Unit has 71 inpatient beds as well as outpatient facilities. Many of the studies include overnight stays. Within the research unit location, you’ll have access to internet, a large relaxation and reading area, and a multimedia room for entertainment. There is also a terrace available for fresh air.

Participants receive financial compensation for their participation. The amount depends on factors like length of the stay, total number of study visits, and the nature of the study procedures.

Frequently asked questions

What is the screening visit?

The screening visit is a key step to joining a clinical trial. At this visit, you will review the informed consent document with members of the study team at the PCRU. The informed consent document describes the details of the clinical trial, including what your rights and responsibilities would be as a participant, and any potential risks, so that you can decide whether you’d like to participate. The study team will answer any questions you may have.

If you decide to participate, you will sign the informed consent document and then undergo study-required tests, procedures, or assessments to confirm whether you meet the eligibility criteria for the study. These may include blood tests, an electrocardiogram (a test that uses sensors attached to the skin to check your heart’s rhythm and electrical activity), and vital signs.

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Can you describe a typical day for a clinical trial participant at the PCRU facility in New Haven, CT?

A typical clinical trial at the New Haven PCRU may have busy days with lots of study procedures, as well as rest days with lots of downtime.

For a typical clinical trial at this facility, your busy day will likely start with an overnight fast. You’ll likely wake up early in the morning for pre-dose activities, which could include an electrocardiogram (a test that uses sensors attached to the skin to check your heart’s rhythm and electrical activity), vital signs, and a blood draw. The study doctor will review your results to confirm you may receive the study drug. Staff will administer your dose according to the study requirements — it could be a tablet or capsule by mouth, a liquid that you drink, an injection, a treatment applied to the skin, or other forms. After that, you’ll likely have procedures throughout the day and into the evening, such as blood draws and safety assessments, meals, and monitoring by the staff to see how you’re feeling.

On rest days, you might have a few morning procedures, but when you are not busy with study activities, you can enjoy free time within the research unit. Within the location you’ll have access to internet, a large relaxation and reading area, and a multimedia room for entertainment. There’s also a terrace available for fresh air.

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Will I have to stay at the PCRU facility the entire time that I’m participating in the clinical trial?

Each clinical study has its own requirements, so the answer to this depends on the study you are participating in. A participant may be required to stay overnight at the PCRU in New Haven, CT, for observation and study procedures. These details are provided in the informed consent document. You may also ask the study team any questions you may have.

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Will I be compensated for participating in a clinical trial at the PCRU?

Participants in clinical trials at the PCRU receive financial compensation for their participation. The amount depends on factors like length of the stay, total number of study visits, and the nature of the study procedures.

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The eligibility criteria for studies at the PCRU include body mass index (BMI). How can I calculate my BMI?

The Centers for Disease Control & Prevention (CDC) provides a calculator that uses your height and weight to determine your BMI. To calculate your BMI, click Learn More.

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Interested in participating?

Call 1-800-254-6398 or click here to see if you may qualify for our research unit’s ongoing clinical trials

or

Explore trials below (click here to filter list)

Recruiting
C4921002B
Oral Study Drug for Heart Failure

The Pfizer Clinical Research Unit is conducting Part B of a clinical trial with healthy volunteers to compare liquid and tablet forms of a study drug for heart failure.

Recruiting healthy volunteers
All Sexes
18 - 65 years
Up to $7,985 upon completion of the study
Recruiting
C5541001D
Oral Study Drug for Weight Management – Part D

The Pfizer Clinical Research Unit is conducting a clinical trial with healthy volunteers of a study drug for obesity and weight management. Part D of this study will look at the study drug combined with an injectable medication.

Recruiting healthy volunteers
All Sexes
18 - 65 years
Up to $11,106 upon completion of the study
Recruiting
C5561001
mRNA Study Vaccine for Influenza (Flu)

The Pfizer Clinical Research Unit is conducting a clinical trial with healthy volunteers of a study vaccine for flu. This study will look at the effects of the study vaccine compared to another vaccine which is used as a control.

Recruiting healthy volunteers
All Sexes
18 - 49 years
Up to $3,000* upon completion of the study
Recruiting
C5541001B
Oral Study Drug for Weight Management – Part B

The Pfizer Clinical Research Unit is conducting a clinical trial with healthy volunteers of a study drug for obesity and weight management. Part B of this study will look at the effects multiple doses of the study drug.

Recruiting healthy volunteers
All Sexes
18 - 65 years
Up to $6,660 upon completion of the study
Recruiting
C4391007
Oral Study Drug for Cancer

The Pfizer Clinical Research Unit is conducting a clinical trial with healthy volunteers of a study drug for certain types of cancer and solid tumors.

Recruiting healthy volunteers
All Sexes
18 - 65 years
Up to $1,750* upon completion of the study
Recruiting
Japanese Volunteers Needed

The Pfizer Clinical Research Unit is seeking healthy Japanese volunteers for upcoming studies.  

Recruiting healthy volunteers
All Sexes
18 - 55 years
Compensation varies by study 

Learn More About the PCRU

: A collection of colorful promotional PCRU-branded items such as colored pens, note pads, and keychain flashlights on a bright pink background.
The New Haven PCRU Loyalty Program is here!

Similar to collecting points or stamps at your favorite coffee shop, PCRU participants can now receive one-of-a-kind gifts as a token of our gratitude for visits to our unit.

John, a healthy volunteer at the Pfizer CRU in New Haven, stands in a purple shirt smiling on a walkway
Finding a greater purpose

When John signed up to participate in his first clinical trial, he figured it would be just that one time. But he so enjoyed the sense of community, and being of service, that he participated in many clinical trials as a healthy volunteer.

clinical trial staff talking in a small meeting room
Rising to the challenge: COVID-19 trials at the New Haven PCRU

Read first-hand accounts from Pfizer CRU colleagues about their experiences on the front lines of COVID-19 research.

PCRU Address

1 Howe St
New Haven, CT 06511
United States

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Hours

Monday - Thursday    7:30 am - 6:30 pm ET
Friday7:30 am - 5:30 pm ET
SaturdayClosed
SundayClosed

 

 

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Our research

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Steps to join a clinical trial

For current clinical trial participants