Learn how Pfizer’s clinical research aims to help advance the treatment of prostate cancer.

Pfizer continues to strive for potential treatment options that may offer new hope for men with prostate cancer. As with many potential treatments, our goal is to help prevent the cancer from advancing further and to improve life expectancy.

We are evaluating study medicines in clinical trials that focus mostly on advanced types of prostate cancer, such as castration-sensitive or castration-resistant prostate cancer. (Learn more about these types of prostate cancer at the bottom of the page.) These studies are researching a study medicine taken along with a currently available standard treatment.

If you or a loved one are considering taking part in a prostate cancer clinical trial, find more information below.

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      6 trials found

      All(6)
      Recruiting(5)
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      Recruiting
      NCT03460977
      PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

      Castration Resistant Prostate Cancer (CRPC), Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL)

      Male or Female
      18+ years
      138study location(s)
      Recruiting
      NCT04557449
      Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

      Liposarcoma, CRC, Prostate Cancer, Breast Neoplasms, Adenocarcinoma of Lung, Solid Tumors

      Male or Female
      18+ years
      74study location(s)
      Recruiting
      NCT04606446
      Study of PF-07248144 in Advanced or Metastatic Solid Tumors

      Locally Advanced or Metastatic ER+ HER2- Breast Cancer, Locally Advanced or Metastatic Castration-resistant Prostate Cancer, Locally Advanced or Metastatic Non-small Cell Lung Cancer

      Male or Female
      18+ years
      92study location(s)
      Recruiting
      NCT06072196
      A Study to Learn About Novel Hormonal Therapies in People With Metastatic Castration-Sensitive Prostate Cancer (mCSPC)

      Prostatic Neoplasms

      Males
      65+ years
      2study location(s)
      Recruiting
      NCT05968599
      A Study to Learn About the Study Medicines Called Enzalutamide and Abiraterone in People With Metastatic Castration-resistant Prostate Cancer

      Prostatic Neoplasms, Castration-Resistant

      Males
      18+ years
      4study location(s)
      Nov 21, 2023 - Planned start date (Not yet recruiting)
      NCT06151418
      A Study to Learn About Novel Hormonal Therapies (NHTs) for Metastatic Castration-sensitive Prostate Cancer (mCSPC) in People Who Were in the Armed Forces

      Prostatic Neoplasms

      Males
      18+ years
      1study location(s)

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      All(6)
      Recruiting(5)
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      Contact us

      For more information about participation in a Pfizer clinical trial, please email or call the Pfizer Clinical Trial Contact Center at 1-800-887-7002.


      About prostate cancer

      Prostate cancer occurs when the cells within the prostate gland start to multiply out of control. It is the second most common cancer in American men, after skin cancer.

      When prostate cancer has not spread beyond the prostate, treatment may first involve surgery or radiation to remove the cancer. Initial treatment may also involve medication that aims to keep levels of the male sex hormones low. This is because prostate cancer growth is often driven by male sex hormones, including testosterone.

      Metastatic castration sensitive prostate cancer occurs when the cancer spreads to other parts of the body, or if the cancer is first diagnosed when it has already spread. This type of prostate cancer is still responsive to hormone therapy.

      If hormone therapy no longer stops or slows the cancer, the condition is known as metastatic castration resistant prostate cancer.