Advancing potential colorectal (colon) cancer treatment options

Learn about Pfizer’s clinical research into a potential targeted therapy for colorectal cancer.

Colorectal cancer, also called colon cancer, is the second leading cause of cancer death in the United States. Pfizer is currently conducting a clinical trial with a focus on colorectal cancer that:

  • is advanced or metastatic (spread to other parts of the body);
  • has a certain type of abnormal gene called “BRAF”

About 10 to 15 percent of people with colorectal cancer have the abnormal BRAF gene, which causes cancer cells to multiply out of control. Identifying whether a person with colorectal cancer has the BRAF gene is an important way to identify an appropriate treatment.

In addition to conducting a clinical trial focused on BRAF-positive colorectal cancer, we are also evaluating other approaches and potential treatments.

If you or a loved one are considering taking part in a colorectal cancer clinical trial, find more information below. With your participation, clinical research might help to identify better treatment options for people with colorectal cancer.

Find a colorectal (colon) cancer clinical trial

Find a Pfizer clinical trial

Refine your search

Filter by

Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
Indicates the current stage of a clinical study and whether it is or will be open for enrollment or in currently active and enrolling in the near future.
  • 50
  • 100
  • 150
  • 200
  • 250+

Searching for Matching Trials ...

9 trials found
All (9) Recruiting (8) Not yet recruiting (1)
  • Save search
  • Saved trials

Contact us

For more information about participation in a Pfizer clinical trial, please email or call the Pfizer Clinical Trial Contact Center at 1-800-887-7002.

About colorectal cancer

Colorectal cancer, also known as colon cancer, occurs when tumors form in the lining of the large intestine. The risk of developing colorectal cancer increases after age 50. Colorectal cancer is common in both men and women.

In addition to age, risk factors include having a family history of colorectal cancer, having ulcerative colitis or Crohn’s disease, eating a diet high in fat, or smoking.

Colorectal cancer symptoms include diarrhea or constipation, a feeling that the bowel does not empty completely, blood in the stool, or frequent gas pains or cramps. There may be no symptoms initially, which is why it is important to have colorectal cancer screening tests.