The purpose of this clinical study is to learn about the safety and effects of the study medicine (called PF-08166744) in healthy adults. This is the first time PF-08166744 will be given to people.
This study is seeking participants who:
- are 18 to 65 years old
- are generally healthy
- have a body mass index (BMI) of 16 to 32 kg/m² and weigh more than 50 kg. Participants will receive either PF-08166744 or placebo. A placebo does not have any medicine in it but looks like the medicine being studied. PF-08166744 or placebo will be given as a shot under the skin. In some study groups, it may be given directly into a vein. Participants will receive either a single dose or 3 doses, depending on the study group they join.
The Investigators will compare the experiences of people receiving study medicine with those receiving placebo. This will help researchers learn about the safety and effects of study medicine.
People receiving a single dose will take part in the study for about 12 to 20 weeks. Those receiving multiple doses will take part for about 22 weeks. During the study, participants will have study visits and tests. These will help check their health and measure the amount of study medicine in their blood.
