Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition
Small Cell Lung Cancer (SCLC)
Sex
Male or Female
Age
18+ years
Healthy participants
No
Visit ClinicalTrials.gov for more information

Eligibility criteria

Study overview

This study is being done to learn more about a new medicine called PF-08634404 and how well it works when given with chemotherapy to adults with extensive-stage small cell lung cancer (ES-SCLC), a fast-growing type of lung cancer that has spread widely in the body.

To join the study, participants must meet the following conditions:

  • Be 18 years or older.
  • Have extensive-stage small cell lung cancer confirmed by lab tests.
  • Have not received chemotherapy or radiation for this type of lung cancer.
  • Be in good physical condition and have healthy organs based on medical tests.


The study has two parts:

  • In the first part, researchers will check how safe the study medicine is and how well people tolerate it when given with chemotherapy.
  • In the second part, they will compare study medicine plus chemotherapy to another approved treatment (atezolizumab plus chemotherapy) to see which works better.


Participants will receive the treatment through IV infusions (medicine given directly into a vein). The treatment will be given in repeated time periods called cycles. Some participants will continue receiving the study medicine alone after the initial treatment.

View locations for this study

Find the closest location, your results will be shown below
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    Miles
    0500

    Nearest Locations found

    32 sites found

    BRCR Coral Springs

    Coral Springs, Florida, United States, 33065
    recruiting status
    Recruiting
    Site Info

    BRCR Global - Coral Springs

    Coral Springs, Florida, United States, 33065
    recruiting status
    Recruiting
    Site Info

    BRCR Global - Tamarac

    Tamarac, Florida, United States, 33321
    recruiting status
    Recruiting
    Site Info

    Doctor's Center Hematology & Oncology Group

    Manati, Puerto Rico, 00674
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group

    Fayetteville, Arkansas, United States, 72703
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group

    Rogers, Arkansas, United States, 72758
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group

    Springdale, Arkansas, United States, 72762
    recruiting status
    Recruiting
    Site Info

    Hospital Oncologico Dr. Isaac Gonzalez-Martinez

    San Juan, Puerto Rico, 00935
    recruiting status
    Recruiting
    Site Info

    Kansai Medical University Hospital

    Hirakata, Osaka, Japan, 573-1191
    recruiting status
    Recruiting
    Site Info

    Mid Florida Hematology and Oncology Center

    Orange City, Florida, United States, 32763
    recruiting status
    Recruiting
    Site Info

    Pan American Center for Oncology Trials, LLC

    San Juan, Puerto Rico, 00909
    recruiting status
    Recruiting
    Site Info

    Pan American Center for Oncology Trials, LLC - Mayaguez Office Mayaguez Medical Center

    Mayagüez, Puerto Rico, 00680
    recruiting status
    Recruiting
    Site Info

    Shizuoka Cancer Center

    Nagaizumi-cho, Shizuoka, Japan, 411-8777
    recruiting status
    Recruiting
    Site Info

    Taipei Medical University Hospital

    Taipei, Taiwan, 110
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Beaumont, Texas, United States, 77702
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Houston, Texas, United States, 77024
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Houston, Texas, United States, 77054
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Pearland, Texas, United States, 77584
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Sugar Land, Texas, United States, 77479
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    The Woodlands, Texas, United States, 77380
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - Gulf Coast

    Webster, Texas, United States, 77598
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - San Antonio

    Fredericksburg, Texas, United States, 78624
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - San Antonio

    New Braunfels, Texas, United States, 78130
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - San Antonio

    San Antonio, Texas, United States, 78217
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - San Antonio

    San Antonio, Texas, United States, 78240
    recruiting status
    Recruiting
    Site Info

    Texas Oncology - San Antonio

    San Antonio, Texas, United States, 78258
    recruiting status
    Recruiting
    Site Info

    Border Medical Oncology Research Unit

    Albury, New South Wales, Australia, 2640
    not yet recruiting status
    Not yet recruiting
    Site Info

    Clario

    Philadelphia, Pennsylvania, United States, 19103
    not yet recruiting status
    Not yet recruiting
    Site Info

    Hospital Universitario 12 de Octubre

    Madrid, Madrid, Comunidad de, Spain, 28041
    not yet recruiting status
    Not yet recruiting
    Site Info

    Hôpital Ambroise Paré

    Boulogne-Billancourt, Île-de-France Region, France, 92100
    not yet recruiting status
    Not yet recruiting
    Site Info

    National Cheng Kung University Hospital

    Tainan, Taiwan, 704302
    not yet recruiting status
    Not yet recruiting
    Site Info

    National Taiwan University Hospital

    Taipei, Taiwan, 10002
    not yet recruiting status
    Not yet recruiting
    Site Info
    • Recruitment Status
    • Site details
    • Study Contact
    • Clinical Trials ID

    Study Locations

    View locations for this studyFind the closest location, your results will be shown belowFind the closest location