A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

Key Inclusion Criteria:

• Children 5 through 11 years of age at their first appointment.
• Children with at least 1 underlying stable medical condition that increases their risk of severe COVID-19, as listed in the protocol.

Key Exclusion Criteria:

• Children who have had confirmed COVID-19 within the last 5 months (150 days).
• Children who have received a COVID-19 vaccine, either as part of a research study or an approved vaccine, within the last 5 months (150 days).
• Children who have received a 2025-2026 seasonal COVID-19 vaccination.
• Children with a history of myocarditis or pericarditis.
• Children with a previous or current diagnosis of Multisystem Inflammatory Syndrome in Children (MIS-C)
• Children with a medical condition wherein they would be considered for a second dose of COVID-19 vaccine to protect against risk of severe COVID-19 based on standard of care.

Refer to the study contact for further eligibility details.