Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition
Metastatic Castration Sensitive Prostate Cancer (mCSPC), Hormone Sensitive Prostate Cancer, Prostate Cancer, Cancer of the Prostate
Sex
Male
Age
18+ years
Healthy participants
No
Visit ClinicalTrials.gov for more information

Eligibility criteria

Study overview

This study will explore whether a combination of the investigational drug mevrometostat (PF-06821497) and enzalutamide will work better than taking enzalutamide alone in participants with mCSPC who are ARPI naïve and have not yet received chemotherapy in the mCSPC setting.

View locations for this study

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    Miles
    0500

    Nearest Locations found

    167 sites found

    ASUIT Trento - Santa Chiara Hospital

    Trento, Italy, 38122
    recruiting status
    Recruiting
    Site Info

    AdventHealth Medical Group Urology of Denver

    Denver, Colorado, United States, 80210
    recruiting status
    Recruiting
    Site Info

    Ankara University Health Practice and Research Hospitals

    Ankara, Turkey (Türkiye)
    recruiting status
    Recruiting
    Site Info

    Asan Medical Center

    Seoul, Seoul-teukbyeolsi [seoul], South Korea, 05505
    recruiting status
    Recruiting
    Site Info

    Auckland City Hospital

    Auckland, New Zealand, 1023
    recruiting status
    Recruiting
    Site Info

    Azienda Ospedaliero Universitaria Maggiore della Carità

    Novara, Italy, 28100
    recruiting status
    Recruiting
    Site Info

    Azienda Ospedaliero-Universitaria San Luigi Gonzaga

    Orbassano, Piedmont, Italy, 10043
    recruiting status
    Recruiting
    Site Info

    CHUVI- Hospital Alvaro Cunqueiro

    Vigo, Pontevedra [pontevedra], Spain, 36312
    recruiting status
    Recruiting
    Site Info

    Cancer Care Specialists of Illinois

    Decatur, Illinois, United States, 62526
    recruiting status
    Recruiting
    Site Info

    Cancer Care Specialists of Illinois

    O'Fallon, Illinois, United States, 62269
    recruiting status
    Recruiting
    Site Info

    Canisius-Wilhelmina Ziekenhuis

    Nijmegen, Gelderland, Netherlands, 6532 SZ
    recruiting status
    Recruiting
    Site Info

    Cedars-Sinai Cancer Beverly Hills

    Beverly Hills, California, United States, 90211
    recruiting status
    Recruiting
    Site Info

    Cedars-Sinai Cancer Beverly Hills (drug treatment and dispensing location)

    Beverly Hills, California, United States, 90211
    recruiting status
    Recruiting
    Site Info

    Cedars-Sinai Cancer at Cedars-Sinai Medical Center

    Los Angeles, California, United States, 90048
    recruiting status
    Recruiting
    Site Info

    Centre Hospitalier Lyon Sud

    Pierre-Bénite, Rhône, France, 69310
    recruiting status
    Recruiting
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    Centro Ricerche Cliniche di Verona

    Verona, Italy, 37134
    recruiting status
    Recruiting
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    Centrum Medyczne MEDYK

    Rzeszów, Poland, 35-326
    recruiting status
    Recruiting
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    Charité Universitaetsmedizin Berlin

    Berlin, Germany, 10117
    recruiting status
    Recruiting
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    Chiba cancer center

    Chiba, Chiba, Japan, 260-8717
    recruiting status
    Recruiting
    Site Info

    Chonnam National University Hwasun Hospital

    Hwasun-gun, Jeonranamdo, South Korea, 58128
    recruiting status
    Recruiting
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    Christchurch Hospital

    Christchurch, Canterbury, New Zealand, 8011
    recruiting status
    Recruiting
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    Chungnam national university hospital

    Junggu, Taejǒn-kwangyǒkshi, South Korea, 35015
    recruiting status
    Recruiting
    Site Info

    Clearview Cancer Institute

    Huntsville, Alabama, United States, 35805
    recruiting status
    Recruiting
    Site Info

    Clearview Cancer Institute (Crestwood)

    Huntsville, Alabama, United States, 35801
    recruiting status
    Recruiting
    Site Info

    Clinical Best Solutions Sp. z o.o. S.K.

    Lublin, Poland, 20-011
    recruiting status
    Recruiting
    Site Info

    Clinical Research Center Spółka z ograniczoną odpowiedzialnością MEDIC-R Sp.k

    Poznan, Greater Poland Voivodeship, Poland, 61-731
    recruiting status
    Recruiting
    Site Info

    Derriford Hospital

    Plymouth, Devon, United Kingdom, Pl6 8DH
    recruiting status
    Recruiting
    Site Info

    EMC Instytut Medyczny S.A.

    Wroclaw, Poland, 54-239
    recruiting status
    Recruiting
    Site Info

    Ewha Womans University Mokdong Hospital

    Seoul, Seoul-teukbyeolsi [seoul], South Korea, 07985
    recruiting status
    Recruiting
    Site Info

    Hadassah Medical Center

    Jerusalem, Jerusalem, Israel, 9112001
    recruiting status
    Recruiting
    Site Info

    Heidelberg University Hospital

    Heidelberg, Baden-Wurttemberg, Germany, 69120
    recruiting status
    Recruiting
    Site Info

    Henri Mondor Hospital

    Créteil, Île-de-France Region, France, 94010
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group, PA

    Fayetteville, Arkansas, United States, 72703
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group, PA

    Rogers, Arkansas, United States, 72758
    recruiting status
    Recruiting
    Site Info

    Highlands Oncology Group, PA

    Springdale, Arkansas, United States, 72762
    recruiting status
    Recruiting
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    Hokkaido University Hospital

    Sapporo, Hokkaido, Japan, 060-8648
    recruiting status
    Recruiting
    Site Info

    Hospital Clinico San Carlos

    Madrid, Spain, 28040
    recruiting status
    Recruiting
    Site Info

    Hospital Clínic de Barcelona

    Barcelona, Catalunya [cataluña], Spain, 08036
    recruiting status
    Recruiting
    Site Info

    Hospital Universitario Ramón y Cajal

    Madrid, Madrid, Comunidad de, Spain, 28034
    recruiting status
    Recruiting
    Site Info

    IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"

    Meldola, Emilia-Romagna, Italy, 47014
    recruiting status
    Recruiting
    Site Info

    IRCCS Istituto Clinico Humanitas

    Rozzano, Milano, Italy, 20089
    recruiting status
    Recruiting
    Site Info

    Imperial College Healthcare NHS Trust, Charing Cross Hospital

    London, Hammersmith and Fulham, United Kingdom, W6 8RF
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Chandler, Arizona, United States, 85224
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Gilbert, Arizona, United States, 85297
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Glendale, Arizona, United States, 85306
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Goodyear, Arizona, United States, 85395
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Mesa, Arizona, United States, 85202
    recruiting status
    Recruiting
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    Ironwood Cancer & Research Centers

    Mesa, Arizona, United States, 85206
    recruiting status
    Recruiting
    Site Info

    Ironwood Cancer & Research Centers

    Phoenix, Arizona, United States, 85028
    recruiting status
    Recruiting
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    Ironwood Cancer & Research Centers

    Scottsdale, Arizona, United States, 85260
    recruiting status
    Recruiting
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    Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

    Chandler, Arizona, United States, 85224
    recruiting status
    Recruiting
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    Istituto Nazionale Tumori Regina Elena

    Rome, ROMA, Italy, 00144
    recruiting status
    Recruiting
    Site Info

    Istituto Oncologico Veneto IOV-IRCCS

    Padova, Italy, 35128
    recruiting status
    Recruiting
    Site Info

    Kanazawa University Hospital

    Kanazawa, Ishikawa-ken, Japan, 920-8641
    recruiting status
    Recruiting
    Site Info

    Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, Taiwan, 807
    recruiting status
    Recruiting
    Site Info

    Keio university hospital

    Shinjuku-ku, Tokyo, Japan, 1608582
    recruiting status
    Recruiting
    Site Info

    Kobe University Hospital

    Kobe, Hyōgo, Japan, 650-0017
    recruiting status
    Recruiting
    Site Info

    Kyungpook National University Chilgok Hospital

    Deagu, Taegu-kwangyǒkshi, South Korea, 41404
    recruiting status
    Recruiting
    Site Info

    MILAB, s.r.o., Urologicka ambulancia

    Prešov, Slovakia, 08 001
    recruiting status
    Recruiting
    Site Info

    Maidstone Hospital

    Maidstone, KENT, United Kingdom, ME16 9QQ
    recruiting status
    Recruiting
    Site Info

    Narodny onkologicky ustav

    Bratislava, Slovakia, 833 10
    recruiting status
    Recruiting
    Site Info

    National Cancer Center

    Goyang-si, Kyǒnggi-do, South Korea, 10408
    recruiting status
    Recruiting
    Site Info

    National Cheng Kung University Hospital

    Tainan, Taiwan, 704
    recruiting status
    Recruiting
    Site Info

    National Hospital Organization Hokkaido Cancer Center

    Sapporo, Hokkaido, Japan, 003-0804
    recruiting status
    Recruiting
    Site Info

    National Hospital Organization Kumamoto Medical Center

    Kumamoto, Japan, 860-0008
    recruiting status
    Recruiting
    Site Info

    National Hospital Organization Kyushu Cancer Center

    Fukuoka, Japan, 811-1395
    recruiting status
    Recruiting
    Site Info

    National Hospital Organization Shikoku Cancer Center

    Matsuyama, Ehime, Japan, 791-0280
    recruiting status
    Recruiting
    Site Info

    National Taiwan University Hospital

    Taipei, Taiwan, 10002
    recruiting status
    Recruiting
    Site Info

    Osaka International Cancer Institute

    Osaka, Japan, 541-8567
    recruiting status
    Recruiting
    Site Info

    Ospedale San Raffaele

    Milan, Italy, 20132
    recruiting status
    Recruiting
    Site Info

    Ospedale Santa Maria delle Croci

    Ravenna, Emilia-Romagna, Italy, 48121
    recruiting status
    Recruiting
    Site Info

    POLIMED CLINIC Sp. z o.o.

    Wroclaw, Lower Silesian Voivodeship, Poland, 53-329
    recruiting status
    Recruiting
    Site Info

    Palmerston North Hospital

    Palmerston North, New Zealand, 4414
    recruiting status
    Recruiting
    Site Info

    Parc de Salut Mar - Hospital del Mar

    Barcelona, Barcelona [barcelona], Spain, 08003
    recruiting status
    Recruiting
    Site Info

    Privatna urologicka ambulancia, s.r.o.

    Trenčín, Slovakia, 911 01
    recruiting status
    Recruiting
    Site Info

    Rabin Medical Center

    Petah Tikva, Central District, Israel, 4941492
    recruiting status
    Recruiting
    Site Info

    Rambam Health Care Campus

    Haifa, Northern District, Israel, 3109601
    recruiting status
    Recruiting
    Site Info

    Reinier de Graaf Ziekenhuis, locatie Delft

    Delft, South Holland, Netherlands, 2625 AD
    recruiting status
    Recruiting
    Site Info

    Ronald Reagan UCLA Medical Center - Drug Information Center

    Los Angeles, California, United States, 90095
    recruiting status
    Recruiting
    Site Info

    Royal Blackburn Hospital

    Blackburn, Blackburn WITH Darwen, United Kingdom, BB2 3HH
    recruiting status
    Recruiting
    Site Info

    Royal Marsden Hospital (Chelsea)

    London, Kensington and Chelsea, United Kingdom, SW3 6JJ
    recruiting status
    Recruiting
    Site Info

    Samsung Medical Center

    Seoul, Seoul-teukbyeolsi [seoul], South Korea, 06351
    recruiting status
    Recruiting
    Site Info

    Seoul National University Bundang Hospital

    Seongnam, Kyǒnggi-do, South Korea, 13620
    recruiting status
    Recruiting
    Site Info

    Seoul National University Hospital

    Seoul, Seoul-teukbyeolsi [seoul], South Korea, 03080
    recruiting status
    Recruiting
    Site Info

    Severance Hospital, Yonsei University Health System

    Seoul, Seoul-teukbyeolsi [seoul], South Korea, 03722
    recruiting status
    Recruiting
    Site Info

    Shaare Zedek Medical Center

    Jerusalem, Jerusalem, Israel, 9013102
    recruiting status
    Recruiting
    Site Info

    Sheba Medical Center

    Ramat Gan, Central District, Israel, 5265601
    recruiting status
    Recruiting
    Site Info

    Sourasky Medical Center

    Tel Aviv, TELL ABĪB, Israel, 6423906
    recruiting status
    Recruiting
    Site Info

    Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie Sp. z o .o.

    Krakow, Poland, 31-826
    recruiting status
    Recruiting
    Site Info

    Szpital Wojewódzki im. Mikołaja Kopernika w Koszalinie

    Koszalin, Poland, 75-581
    recruiting status
    Recruiting
    Site Info

    Szpitale Pomorskie Sp. z o.o.

    Gdynia, Poland, 81-519
    recruiting status
    Recruiting
    Site Info

    Taichung Veterans General Hospital

    Taichung, Taiwan, 407
    recruiting status
    Recruiting
    Site Info

    Tauranga Hospital

    Tauranga, Bay of Plenty, New Zealand, 3112
    recruiting status
    Recruiting
    Site Info

    Tergooiziekenhuizen, locatie Hilversum

    Hilversum, North Holland, Netherlands, 1212 VG
    recruiting status
    Recruiting
    Site Info

    The Christie NHS Foundation Trust

    Manchester, United Kingdom, M20 4BX
    recruiting status
    Recruiting
    Site Info

    The University of Osaka Hospital

    Suita, Osaka, Japan, 565-0871
    recruiting status
    Recruiting
    Site Info

    Torbay Hospital

    Torquay, Devon, United Kingdom, TQ2 7AA
    recruiting status
    Recruiting
    Site Info

    UCLA Department of Medicine - Hematology/Oncology

    Los Angeles, California, United States, 90095
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology

    Los Angeles, California, United States, 90095
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Alhambra

    Alhambra, California, United States, 91801
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Atascadero

    Atascadero, California, United States, 93422
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Beverly Hills

    Beverly Hills, California, United States, 90212
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Burbank

    Burbank, California, United States, 91505
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Encino

    Encino, California, United States, 91436
    recruiting status
    Recruiting
    Site Info

    UCLA Hematology/Oncology - Irvine

    Irvine, California, United States, 92604
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Laguna Hills

    Laguna Hills, California, United States, 92653
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Marina del Rey

    Marina del Rey, California, United States, 90292
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Pasadena

    Pasadena, California, United States, 91105
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Porter Ranch

    Porter Ranch, California, United States, 91326
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - San Luis Obispo

    San Luis Obispo, California, United States, 93401
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Santa Barbara

    Santa Barbara, California, United States, 93101
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Santa Clarita

    Valencia, California, United States, 91355
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Torrance

    Torrance, California, United States, 90505
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Ventura

    Ventura, California, United States, 93003
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology - Westlake

    Westlake Village, California, United States, 91361
    recruiting status
    Recruiting
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    UCLA Hematology/Oncology- Santa Monica

    Santa Monica, California, United States, 90404
    recruiting status
    Recruiting
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    Universitaetsklinikum Hamburg-Eppendorf

    Hamburg, Germany, 20246
    recruiting status
    Recruiting
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    Universitaetsklinikum Ulm

    Ulm, Baden-Wurttemberg, Germany, 89081
    recruiting status
    Recruiting
    Site Info

    Urologie Neandertal - Praxis Mettmann

    Mettmann, North Rhine-Westphalia, Germany, 40822
    recruiting status
    Recruiting
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    Velindre Cancer Centre

    Cardiff, Cardiff [caerdydd Gb-crd], United Kingdom, CF14 2TL
    recruiting status
    Recruiting
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    Vychodoslovensky onkologicky ustav, a.s.

    Košice, Slovakia, 041 91
    recruiting status
    Recruiting
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    Waikato Hospital

    Hamilton, Waikato Region, New Zealand, 3204
    recruiting status
    Recruiting
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    Yamagata University Hospital

    Yamagata, Japan, 990-9585
    recruiting status
    Recruiting
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    Yitzhak Shamir Medical Center

    Ẕerifin, Central District, Israel, 70300
    recruiting status
    Recruiting
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    Yokohama City University Medical Center

    Yokohama, Kanagawa, Japan, 232-0024
    recruiting status
    Recruiting
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    Yokosuka Kyosai Hospital

    Yokosuka, Kanagawa, Japan, 238-8558
    recruiting status
    Recruiting
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    Zachodniopomorskie Centrum Onkologii

    Szczecin, Zachodniopomorskie Voivodeship, Poland, 71-730
    recruiting status
    Recruiting
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    Alexandra General Hospital of Athens

    Athens, Attikí, Greece, 115 28
    not yet recruiting status
    Not yet recruiting
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    Althaia, Xarxa Assistencial Universitària de Manresa

    Manresa, Barcelona, Spain, 08243
    not yet recruiting status
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    Athens Medical Center S.A -European Interbalkan Medical Center

    Thessaloniki, Greece, 57001
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    Chang Gung Medical Foundation-Linkou Branch

    Guishan Dist., Taoyuan, Taiwan, 333034
    not yet recruiting status
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    Dicle Üniversitesi

    Diyarbakır, Turkey (Türkiye), 21200
    not yet recruiting status
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    Dokuz Eylul Universitesi Hastanesi

    Izmir, İ̇zmir, Turkey (Türkiye), 35340
    not yet recruiting status
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    Evelyn H. Lauder Breast and Imaging Center (BAIC).

    New York, New York, United States, 10065
    not yet recruiting status
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    Fundación Instituto Valenciano de Oncología

    Valencia, Valenciana, Comunitat, Spain, 46009
    not yet recruiting status
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    General Hospital of Athens "G. Gennimatas"

    Athens, Greece, 115 27
    not yet recruiting status
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    Gulhane Egitim Arastirma Hastanesi

    Ankara, Turkey (Türkiye), 06010
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    Gustave Roussy

    Villejuif, Val-de-marne, France, 94800
    not yet recruiting status
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    Guy's & St Thomas' NHS Foundation Trust

    London, London, CITY of, United Kingdom, SE1 9RT
    not yet recruiting status
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    Hospital General Universitario de Valencia

    Valencia, Spain, 46014
    not yet recruiting status
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    Hospital Universitario 12 de Octubre

    Madrid, Madrid, Comunidad de, Spain, 28041
    not yet recruiting status
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    Hospital Universitario Fundación Jiménez Díaz

    Madrid, Spain, 28040
    not yet recruiting status
    Not yet recruiting
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    Hospital Universitario Virgen de la Victoria

    Málaga, Málaga, Spain, 29010
    not yet recruiting status
    Not yet recruiting
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    I.E.U. Medical Point Hastanesi

    Izmir, İ̇zmir, Turkey (Türkiye), 009035575
    not yet recruiting status
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    IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola

    Bologna, Italy, 40138
    not yet recruiting status
    Not yet recruiting
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    Inselspital Bern

    Bern, Canton of Bern, Switzerland, 3010
    not yet recruiting status
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    Institut de Cancérologie de l'Ouest

    Angers, France, 49100
    not yet recruiting status
    Not yet recruiting
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    Kantonsspital Winterthur

    Winterthur, Switzerland, 8401
    not yet recruiting status
    Not yet recruiting
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    MSK Basking Ridge

    Basking Ridge, New Jersey, United States, 07920
    not yet recruiting status
    Not yet recruiting
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    MSK Bergen

    Montvale, New Jersey, United States, 07645
    not yet recruiting status
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    MSK Commack

    Commack, New York, United States, 11725
    not yet recruiting status
    Not yet recruiting
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    MSK Monmouth

    Middletown, New Jersey, United States, 07748
    not yet recruiting status
    Not yet recruiting
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    MSKCC-Westchester (500 Westchester Ave.)

    Harrison, New York, United States, 10604
    not yet recruiting status
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    Memorial Ankara Hastanesi

    Ankara, Turkey (Türkiye), 06520
    not yet recruiting status
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    Memorial Sloan Kettering Cancer Center (IDS Pharmacy)

    Long Island City, New York, United States, 11101
    not yet recruiting status
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    Memorial Sloan Kettering Cancer Center - Main Campus

    New York, New York, United States, 10065
    not yet recruiting status
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    Metropolitan Hospital

    Athens, Greece, 18547
    not yet recruiting status
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    Michigan Institute of Urology, PC

    Troy, Michigan, United States, 48084
    not yet recruiting status
    Not yet recruiting
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    Sidney Kimmel Center for Prostate and Urological Cancers - Memorial Sloan Kettering Cancer Center

    New York, New York, United States, 10065
    not yet recruiting status
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    Studienpraxis Urologie

    Nürtingen, Baden-Wurttemberg, Germany, 72622
    not yet recruiting status
    Not yet recruiting
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    Taipei Veterans General Hospital

    Taipei, Taiwan, 11217
    not yet recruiting status
    Not yet recruiting
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    Universitaetsmedizin Goettingen

    Göttingen, Lower Saxony, Germany, 37075
    not yet recruiting status
    Not yet recruiting
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    UniversitätsSpital Zürich

    Zurich, Switzerland, 8091
    not yet recruiting status
    Not yet recruiting
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    Universitätsklinikum Münster - Albert Schweitzer Campus

    Münster, North Rhine-Westphalia, Germany, 48149
    not yet recruiting status
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    Universitätsklinikum Schleswig Holstein

    Lübeck, Schleswig-Holstein, Germany, 23538
    not yet recruiting status
    Not yet recruiting
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    Western General Hospital

    Edinburgh, Midlothian, United Kingdom, EH4 2XU
    not yet recruiting status
    Not yet recruiting
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    İ.A.Ü VM Medical Park Florya Hastanesi

    Istanbul, İ̇stanbul, Turkey (Türkiye), 34295
    not yet recruiting status
    Not yet recruiting
    Site Info
    • Recruitment Status
    • Site details
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    • Clinical Trials ID

    Study Locations

    View locations for this studyFind the closest location, your results will be shown belowFind the closest location