This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

AZORG Campus Aalst-Moorselbaan

Aalst, Belgium, 9300

Recruiting

Advanced Urology Institute, LLC

Largo, Florida, United States, 33771

Recruiting

AdventHealth Medical Group Urology of Denver

Denver, Colorado, United States, 80210

Recruiting

Associated Urological Specialists - Chicago Ridge

Chicago Ridge, Illinois, United States, 60415

Recruiting

Blue Ridge Cancer Care

Blacksburg, Virginia, United States, 24060

Recruiting

Blue Ridge Cancer Care

Low Moor, Virginia, United States, 24457

Recruiting

Blue Ridge Cancer Care

Roanoke, Virginia, United States, 24014

Recruiting

Blue Ridge Cancer Care

Salem, Virginia, United States, 24153

Recruiting

Blue Ridge Cancer Care

Wytheville, Virginia, United States, 24382

Recruiting

Cancer Care Specialists of Illinois

Decatur, Illinois, United States, 62526

Recruiting

Cancer Care Specialists of Illinois

O'Fallon, Illinois, United States, 62269

Recruiting

Carolina Urologic Research Center, LLC

Myrtle Beach, South Carolina, United States, 29572

Recruiting

Cedars-Sinai Cancer Beverly Hills

Beverly Hills, California, United States, 90211

Recruiting

Cedars-Sinai Cancer Beverly Hills (drug treatment and dispensing location)

Beverly Hills, California, United States, 90211

Recruiting

Cedars-Sinai Cancer at Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048

Recruiting

Chiba cancer center

Chiba, Chiba, Japan, 260-8717

Recruiting

Clearview Cancer Institute

Huntsville, Alabama, United States, 35805

Recruiting

Clearview Cancer Institute (Crestwood)

Huntsville, Alabama, United States, 35801

Recruiting

Duke Cancer Center Cary

Cary, North Carolina, United States, 27518

Recruiting

Duke Cancer Center Raleigh

Raleigh, North Carolina, United States, 27609

Recruiting

Duke Raleigh Hospital

Raleigh, North Carolina, United States, 27609

Recruiting

Duke University

Durham, North Carolina, United States, 27713

Recruiting

Duke University Medical Center (location of scans)

Durham, North Carolina, United States, 27710

Recruiting

Duke University Medical Center - Duke Cancer Center

Durham, North Carolina, United States, 27710

Recruiting

Duke University Medical Center - Duke University Hospital (location of scans)

Durham, North Carolina, United States, 27710

Recruiting

Duke Women's Cancer Care Raleigh (Pharmacy location and location of CT, MRI and Bone scan machines)

Raleigh, North Carolina, United States, 27609

Recruiting

Evelyn H. Lauder Breast and Imaging Center (BAIC).

New York, New York, United States, 10065

Recruiting

Grand Strand Medical Center

Myrtle Beach, South Carolina, United States, 295724607

Recruiting

Highlands Oncology Group, PA

Fayetteville, Arkansas, United States, 72703

Recruiting

Highlands Oncology Group, PA

Rogers, Arkansas, United States, 72758

Recruiting

Highlands Oncology Group, PA

Springdale, Arkansas, United States, 72762

Recruiting

Hokkaido University Hospital

Sapporo, Hokkaido, Japan, 060-8648

Recruiting

Huntsman Cancer Institute

Salt Lake City, Utah, United States, 84112

Recruiting

Integrated Medical Professionals

Lake Success, New York, United States, 11042

Recruiting

Integrated Medical Professionals

Seaford, New York, United States, 11783

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Chandler, Arizona, United States, 85224

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Gilbert, Arizona, United States, 85297

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Glendale, Arizona, United States, 85306

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Goodyear, Arizona, United States, 85395

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Mesa, Arizona, United States, 85202

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Mesa, Arizona, United States, 85206

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Phoenix, Arizona, United States, 85028

Recruiting

Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers

Scottsdale, Arizona, United States, 85260

Recruiting

Kanazawa University Hospital

Kanazawa, Ishikawa-ken, Japan, 920-8641

Recruiting

Keio university hospital

Shinjuku-ku, Tokyo, Japan, 1608582

Recruiting

Kobe University Hospital

Kobe, Hyōgo, Japan, 650-0017

Recruiting

MSK Basking Ridge

Basking Ridge, New Jersey, United States, 07920

Recruiting

MSK Bergen

Montvale, New Jersey, United States, 07645

Recruiting

MSK Commack

Commack, New York, United States, 11725

Recruiting

MSK Monmouth

Middletown, New Jersey, United States, 07748

Recruiting

MSK Nassau.

Uniondale, New York, United States, 11553

Recruiting

MSKCC-Westchester (500 Westchester Ave.)

Harrison, New York, United States, 10604

Recruiting

Memorial Sloan Kettering Cancer Center (IDS Pharmacy)

Long Island City, New York, United States, 11101

Recruiting

Memorial Sloan Kettering Cancer Center - Main Campus

New York, New York, United States, 10065

Recruiting

Michigan Institute of Urology, PC

Troy, Michigan, United States, 48084

Recruiting

MidLantic urology

Bala-Cynwyd, Pennsylvania, United States, 19004

Recruiting

Montefiore Einstein Comprehensive Cancer Center

The Bronx, New York, United States, 10461

Recruiting

Montefiore Medical Center- Montefiore Medical Park

The Bronx, New York, United States, 10461

Recruiting

National Hospital Organization Hokkaido Cancer Center

Sapporo, Hokkaido, Japan, 003-0804

Recruiting

National Hospital Organization Kumamoto Medical Center

Kumamoto, Japan, 860-0008

Recruiting

National Hospital Organization Kyushu Cancer Center

Fukuoka, Japan, 811-1395

Recruiting

National Hospital Organization Shikoku Cancer Center

Matsuyama, Ehime, Japan, 791-0280

Recruiting

Northwest Medical Specialties, PLLC

Bonney Lake, Washington, United States, 98391

Recruiting

Northwest Medical Specialties, PLLC

Federal Way, Washington, United States, 98003

Recruiting

Northwest Medical Specialties, PLLC

Gig Harbor, Washington, United States, 98332

Recruiting

Northwest Medical Specialties, PLLC

Puyallup, Washington, United States, 98373

Recruiting

Northwest Medical Specialties, PLLC

Tacoma, Washington, United States, 98405

Recruiting

Osaka International Cancer Institute

Osaka, Japan, 541-8567

Recruiting

Parkway Surgery Center

Myrtle Beach, South Carolina, United States, 29572

Recruiting

Ronald Reagan UCLA Medical Center - Drug Information Center

Los Angeles, California, United States, 90095

Recruiting

Sidney Kimmel Center for Prostate and Urological Cancers - Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Recruiting

Tennessee Oncology Hendersonville

Hendersonville, Tennessee, United States, 37075

Recruiting

Tennessee Oncology PLLC

Chattanooga, Tennessee, United States, 37404

Recruiting

Tennessee Oncology, PLLC - Chattanooga Downtown

Chattanooga, Tennessee, United States, 37403

Recruiting

Tennessee Oncology, PLLC - Chattanooga East

Chattanooga, Tennessee, United States, 37421

Recruiting

Tennessee Oncology, PLLC - Chattanooga Med Park II

Chattanooga, Tennessee, United States, 37404

Recruiting

Tennessee Oncology, PLLC - Chattanooga Memorial

Chattanooga, Tennessee, United States, 37404

Recruiting

Tennessee Oncology, PLLC - Cleveland

Cleveland, Tennessee, United States, 37311

Recruiting

Tennessee Oncology, PLLC - Cookeville

Cookeville, Tennessee, United States, 38501

Recruiting

Tennessee Oncology, PLLC - Dalton

Dalton, Georgia, United States, 30720

Recruiting

Tennessee Oncology, PLLC - Dickson

Dickson, Tennessee, United States, 37055

Recruiting

Tennessee Oncology, PLLC - Franklin

Franklin, Tennessee, United States, 37067

Recruiting

Tennessee Oncology, PLLC - Gallatin

Gallatin, Tennessee, United States, 37066

Recruiting

Tennessee Oncology, PLLC - Investigational Drug Services

Nashville, Tennessee, United States, 37203

Recruiting

Tennessee Oncology, PLLC - Lebanon

Lebanon, Tennessee, United States, 37090

Recruiting

Tennessee Oncology, PLLC - Mount Juliet

Mount Juliet, Tennessee, United States, 37122

Recruiting

Tennessee Oncology, PLLC - Murfreesboro

Murfreesboro, Tennessee, United States, 37129

Recruiting

Tennessee Oncology, PLLC - Nashville Elliston Place Plaza Medical Oncology & Hematology Clinic

Nashville, Tennessee, United States, 37203

Recruiting

Tennessee Oncology, PLLC - Nashville Saint Thomas West

Nashville, Tennessee, United States, 37205

Recruiting

Tennessee Oncology, PLLC - Nashville Skyline

Nashville, Tennessee, United States, 37207

Recruiting

Tennessee Oncology, PLLC - Nashville Southern Hills

Nashville, Tennessee, United States, 37211

Recruiting

Tennessee Oncology, PLLC - Ringgold

Ringgold, Georgia, United States, 30736

Recruiting

Tennessee Oncology, PLLC - Shelbyville

Shelbyville, Tennessee, United States, 37160

Recruiting

Tennessee Oncology, PLLC - Smyrna

Smyrna, Tennessee, United States, 37167

Recruiting

The Centers for Advanced Urology d/b/a Keystone Urology Specialist

Lancaster, Pennsylvania, United States, 17604

Recruiting

The University of Osaka Hospital

Suita, Osaka, Japan, 565-0871

Recruiting

The West Clinic, PLLC dba West Cancer Center

Germantown, Tennessee, United States, 38138

Recruiting

TriState Urologic Services PSC Inc. dba The Urology Group

Cincinnati, Ohio, United States, 45212

Recruiting

UCLA Department of Medicine - Hematology/Oncology

Los Angeles, California, United States, 90095

Recruiting

UCLA Hematology/Oncology

Los Angeles, California, United States, 90095

Recruiting

UCLA Hematology/Oncology - Alhambra

Alhambra, California, United States, 91801

Recruiting

UCLA Hematology/Oncology - Atascadero

Atascadero, California, United States, 93422

Recruiting

UCLA Hematology/Oncology - Beverly Hills

Beverly Hills, California, United States, 90212

Recruiting

UCLA Hematology/Oncology - Burbank

Burbank, California, United States, 91505

Recruiting

UCLA Hematology/Oncology - Encino

Encino, California, United States, 91436

Recruiting

UCLA Hematology/Oncology - Irvine

Irvine, California, United States, 92604

Recruiting

UCLA Hematology/Oncology - Laguna Hills

Laguna Hills, California, United States, 92653

Recruiting

UCLA Hematology/Oncology - Marina del Rey

Marina del Rey, California, United States, 90292

Recruiting

UCLA Hematology/Oncology - Pasadena

Pasadena, California, United States, 91105

Recruiting

UCLA Hematology/Oncology - Porter Ranch

Porter Ranch, California, United States, 91326

Recruiting

UCLA Hematology/Oncology - San Luis Obispo

San Luis Obispo, California, United States, 93401

Recruiting

UCLA Hematology/Oncology - Santa Barbara

Santa Barbara, California, United States, 93101

Recruiting

UCLA Hematology/Oncology - Santa Clarita

Valencia, California, United States, 91355

Recruiting

UCLA Hematology/Oncology - Torrance

Torrance, California, United States, 90505

Recruiting

UCLA Hematology/Oncology - Ventura

Ventura, California, United States, 93003

Recruiting

UCLA Hematology/Oncology - Westlake

Westlake Village, California, United States, 91361

Recruiting

UCLA Hematology/Oncology- Santa Monica

Santa Monica, California, United States, 90404

Recruiting

UH Minoff Health Center at Chagrin Highlands

Orange, Ohio, United States, 44122

Recruiting

US Oncology Investigational Product Center (IPC)

Irving, Texas, United States, 75063

Recruiting

UVA Health Cancer Care Pantops

Charlottesville, Virginia, United States, 22911

Recruiting

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106

Recruiting

University Hospitals Seidman Cancer Center at UH Avon Health Center

Avon, Ohio, United States, 44011

Recruiting

University Hospitals Seidman Cancer Center at UH Mentor Health Center

Mentor, Ohio, United States, 44060

Recruiting

University of Rochester Medical Center

Rochester, New York, United States, 14642

Recruiting

University of Rochester, Cancer Center Pharmacy (Investigational Product)

Rochester, New York, United States, 14642

Recruiting

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390

Recruiting

University of Texas Southwestern Medical Center - Simmons Cancer Center

Dallas, Texas, United States, 75235

Recruiting

University of Texas Southwestern Medical Center - William P. Clements, Jr., University Hospital

Dallas, Texas, United States, 75235

Recruiting

University of Texas Southwestern Medical Center-Zale Lipshy University Hospital

Dallas, Texas, United States, 75390

Recruiting

University of Texas Southwestern Simmons Cancer Center - Fort Worth

Fort Worth, Texas, United States, 76104

Recruiting

University of Texas Southwestern Simmons Cancer Center - Redbird

Dallas, Texas, United States, 75237

Recruiting

University of Texas Southwestern Simmons Cancer Center - Richardson/Plano

Richardson, Texas, United States, 75080

Recruiting

University of Virginia

Charlottesville, Virginia, United States, 22908

Recruiting

University of Virginia Comprehensive Cancer Center

Charlottesville, Virginia, United States, 22903

Recruiting

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

Madison, Wisconsin, United States, 53718

Recruiting

University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, United States, 53792

Recruiting

Urology Associates, P.C.

Nashville, Tennessee, United States, 37209

Recruiting

Yamagata University Hospital

Yamagata, Japan, 990-9585

Recruiting

Yokohama City University Medical Center

Yokohama, Kanagawa, Japan, 232-0024

Recruiting

Yokosuka Kyosai Hospital

Yokosuka, Kanagawa, Japan, 238-8558

Recruiting