Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition
Migraine
Sex
Male or Female
Age
12 - 17 years
Healthy participants
No
Visit ClinicalTrials.gov for more information

Eligibility criteria

Study overview

The purpose of this study is to learn about the effect of a study medicine called rimegepant in adolescents who have frequent migraine attacks.

Rimegepant is a tablet that dissolves when you put it on or under your tongue.

The study will enroll participants who have headache for 15 days (or more) every month, of which 8 days (or more) of migraine every month, and each untreated attack lasts for an average of 4-72 hours

In the 1st part of the study approximately half of the participants will receive a rimegepant tablet every other day, and approximately half of the participants will receive an inactive oral tablet (that looks the same as the rimegepant tablet) every other day.

Participant experiences when they are taking the study medicine will be compared to when they are taking the inactive tablet. This will help to determine if the study medicine is safe and effective. The 1st phase of the study will last 3 months.

In the 2nd part of the study all the participants who stay on study will receive rimegepant tablet every other day. This 2nd phase of the study will last 1 year. This will help determine if the study medicine is safe when taken for a long period.

Those who will participate in both phases will have up to 19 visits at the study clinic, about one every 4 weeks (this may vary from 2 to 8 weeks interval during the study). Home health visits may occur as well. A health check and blood sample will be conducted at all visits. Participants will have to complete a daily diary to record the migraine attacks.

View locations for this study

Find the closest location, your results will be shown below
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    Miles
    0500

    Nearest Locations found

    48 sites found

    Adult & Child Neurology Medical Associates

    Long Beach, California, United States, 90806
    recruiting status
    Recruiting
    Site Info

    Affiliated Hospital of Jiangsu University

    Zhenjiang, Jiangsu, China, 212001
    recruiting status
    Recruiting
    Site Info

    Anhui Provincial Hospital

    Hefei, China, 230001
    recruiting status
    Recruiting
    Site Info

    Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, United States, 60611
    recruiting status
    Recruiting
    Site Info

    Avera Medical Group Pediatric Specialists

    Sioux Falls, South Dakota, United States, 57105
    recruiting status
    Recruiting
    Site Info

    Avera Medical Group Pediatrics - Dawley Farm

    Sioux Falls, South Dakota, United States, 57110
    recruiting status
    Recruiting
    Site Info

    Avera Research Institute - Sioux Falls

    Sioux Falls, South Dakota, United States, 57108
    recruiting status
    Recruiting
    Site Info

    CaRe Clinic

    Red Deer, Alberta, Canada, T4P 1K4
    recruiting status
    Recruiting
    Site Info

    Centrum Medyczne Hope Clinic Sebastian Szklener

    Lublin, Lublin Voivodeship, Poland, 20-701
    recruiting status
    Recruiting
    Site Info

    Chicago Headache Center and Research Institute

    Chicago, Illinois, United States, 60657
    recruiting status
    Recruiting
    Site Info

    Chopda Medicare & Research Centre Pvt. Ltd; Magnum Heart Institute

    Nashik, Maharashtra, India, 422005
    recruiting status
    Recruiting
    Site Info

    Clinvest Headlands Llc

    Springfield, Missouri, United States, 65807
    recruiting status
    Recruiting
    Site Info

    Debreceni Egyetem Klinikai Kozpont

    Debrecen, Hungary, 4032
    recruiting status
    Recruiting
    Site Info

    Detska fakultna nemocnica s poliklinikou Banska Bystrica

    Banská Bystrica, Slovakia, 97409
    recruiting status
    Recruiting
    Site Info

    Detska nemocnice FN Brno

    Brno, Brno-město, Czechia, 613 00
    recruiting status
    Recruiting
    Site Info

    Dr Sękowska Leczenie Bólu

    Warsaw, Masovian Voivodeship, Poland, 01-018
    recruiting status
    Recruiting
    Site Info

    Dr. Kenessey Albert Kórház

    Balassagyarmat, Nógrád megye, Hungary, 2660
    recruiting status
    Recruiting
    Site Info

    Duke Health Center Creekstone

    Durham, North Carolina, United States, 27703
    recruiting status
    Recruiting
    Site Info

    Duke Lenox Baker Children's

    Durham, North Carolina, United States, 27705
    recruiting status
    Recruiting
    Site Info

    Fakultni nemocnice Hradec Kralove

    Hradec Králové, Hradec Králové, Czechia, 500 05
    recruiting status
    Recruiting
    Site Info

    Fakultni nemocnice Ostrava

    Ostrava, Moravian-Silesian Region, Czechia, 708 52
    recruiting status
    Recruiting
    Site Info

    Hospital Universitari Vall d'Hebron

    Barcelona, Barcelona [barcelona], Spain, 08035
    recruiting status
    Recruiting
    Site Info

    Hospital Universitari i Politecnic La Fe

    Valencia, Spain, 46026
    recruiting status
    Recruiting
    Site Info

    Hospital Universitario HM Puerta del Sur

    Madrid, Madrid, Comunidad de, Spain, 28938
    recruiting status
    Recruiting
    Site Info

    Hospital Universitario HM Sanchinarro

    Madrid, Spain, 28050
    recruiting status
    Recruiting
    Site Info

    I.C.O.T. Università La Sapienza

    Latina, Italy, 04100
    recruiting status
    Recruiting
    Site Info

    IRCCS Istituto Neurologico Carlo Besta

    Milan, Lombardy, Italy, 20133
    recruiting status
    Recruiting
    Site Info

    KONZILIUM s.r.o.

    Dubnica nad Váhom, Slovakia
    recruiting status
    Recruiting
    Site Info

    MedicArt Sp. z o. o.

    Wroclaw, Lower Silesian Voivodeship, Poland, 53-025
    recruiting status
    Recruiting
    Site Info

    Michigan Headache & Neurological Institute

    Ann Arbor, Michigan, United States, 48104
    recruiting status
    Recruiting
    Site Info

    Nagaseki Headache Clinic

    Kai, Yamanashi, Japan, 400-0124
    recruiting status
    Recruiting
    Site Info

    Narodny ustav detskych chorob

    Bratislava, Slovakia, 833 40
    recruiting status
    Recruiting
    Site Info

    New Children's Hospital

    Helsinki, Finland, 00290
    recruiting status
    Recruiting
    Site Info

    OnSite Clinical Solutions

    Charlotte, North Carolina, United States, 28211
    recruiting status
    Recruiting
    Site Info

    Ospedale San Paolo Bari

    Bari, Apulia, Italy, 70132
    recruiting status
    Recruiting
    Site Info

    Peking University People's Hospital

    Beijing, Beijing Municipality, China, 100044
    recruiting status
    Recruiting
    Site Info

    Rutgers University

    New Brunswick, New Jersey, United States, 08901
    recruiting status
    Recruiting
    Site Info

    Semmelweis Egyetem

    Budapest, Hungary, 1094
    recruiting status
    Recruiting
    Site Info

    Shanghai Children's Hospital

    Shanghai, China, 200062
    recruiting status
    Recruiting
    Site Info

    Stollery Children's Hospital

    Edmonton, Alberta, Canada, T6G 2B7
    recruiting status
    Recruiting
    Site Info

    Terveystalo Pulssi

    Turku, Finland, 20100
    recruiting status
    Recruiting
    Site Info

    The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China, 400016
    recruiting status
    Recruiting
    Site Info

    The University of Texas Health Science Center at Houston

    Houston, Texas, United States, 77030
    recruiting status
    Recruiting
    Site Info

    Tokyo Headache Clinic

    Shibuya-ku, Tokyo, Japan, 151-0051
    recruiting status
    Recruiting
    Site Info

    Tominaga Clinic

    Osaka, Osaka, Japan, 556-0015
    recruiting status
    Recruiting
    Site Info

    University Of Alberta Hospital

    Edmonton, Alberta, Canada, T6G 1W9
    recruiting status
    Recruiting
    Site Info

    Univerzitna nemocnica Martin

    Martin, Slovakia, 036 59
    recruiting status
    Recruiting
    Site Info

    Wake Forest University Baptist Medical Center ( WFUBMC )

    Winston-Salem, North Carolina, United States, 27157
    recruiting status
    Recruiting
    Site Info
    • Recruitment Status
    • Site details
    • Study Contact
    • Clinical Trials ID

    Study Locations

    View locations for this studyFind the closest location, your results will be shown belowFind the closest location