The Pfizer New Haven Clinical Research Unit is conducting a clinical trial of a study vaccine for flu. This study will look at the effects of the study vaccine compared to another vaccine which is used as a control.

Vaccines are one of the greatest public health advances of all time. Similar to clean water and good sanitation, vaccines safeguard our communities and help people stay well, productive, and active.

While several illnesses have been partially or fully eliminated by vaccines, there is still much work to be done for other infections worldwide, like influenza or flu which currently affects about a billion people annually. By joining a vaccine clinical trial at the PCRU, you could be part of the next vaccine breakthrough.

Read more about how you can become a participant below.

Who may participate

We know how important vaccines are for protecting our patients and their loved ones. But before any vaccine can be given to those who need it, it must be studied in a series of clinical trials with volunteers like you.

This study is seeking healthy adult volunteers, meaning that the participants will not have the condition being studied and are in overall good health. In addition to the criteria listed, participants must meet the following requirements: 

  • Willing to receive a study vaccine
  • Willing and able to come to our facility in New Haven, CT*
  • Willing and able to comply with all study procedures

*participants may be eligible to receive a bonus for travel, ask our staff for details

There are other requirements for participation in this study. The study staff will explain these to you during the screening process.

Do you know someone who may meet these requirements? Refer a friend and you may be eligible to receive a bonus. 

Learn more




18-49 years


All sexes

Referral bonus

Up to $100

Each clinical study has its own guidelines for who can participate, called eligibility criteria. However, only the research study staff can determine if you qualify to enroll in the study.

What to expect

If this study may be a fit for you, you’ll be invited to a screening visit at our facility in New Haven, CT. If you qualify for the study, screening and dosing may happen on the same day, or there may be a period of up to 28 days before dosing.

If you choose to participate, you will receive a single dose of either the study vaccine or another vaccine, administered as an injection in the muscle of your upper arm. You will have a follow-up visit about 1 week later. Then about 3 weeks after the first dose, you will return to the PCRU to receive a second dose of the study vaccine or a placebo, again administered by injection into the upper arm. You will then have 4 more follow-up visits scheduled over the next ~6 months. The schedule for these will be provided to you when you schedule your appointment.

It is very important to complete each visit on time, so please let our team know if you have any issues with the schedule as soon as possible.

Throughout the study, staff will closely monitor your health status and collect data, such as the levels of immune markers in your blood. You may also be asked to complete an electronic diary to log things like how you feel and your daily temperature in between trips to the unit.

*When screening and first study dose occur separately, the additional visit will be compensated at a rate of $300.

Required site visits

7 planned visits**

How long are the visits?

About 2-4 hours each

How long is this study?

About 7 months


Up to $3,000** upon completion of the study

All of the study procedures will be clearly explained to you during screening.

Get started — See if you may be eligible

A first step as you consider this study is to answer some questions about your health and medical history. You may complete this short 5-minute online questionnaire to see if you may be eligible, or you may call the PCRU directly to complete this process. If your answers show the study might be a good fit for you, you may choose to submit your information to us.

You will then be asked to provide your contact information for one of our staff to contact you and discuss the next steps. If you’re interested, we will do a more detailed review of your medical history to see if you are able to participate. Only the PCRU staff can determine if you meet the study’s eligibility criteria and are able to enroll in the study.

Your answers to these initial questions will only be linked to you if your responses indicate that you may be eligible to participate in this study and you choose to share your contact information with the study team. Pfizer study team members and our partners will have access to reports containing aggregated data that will not be directly linked back to you.

The PCRU Loyalty Program has arrived!

Our new Loyalty Program offers unique tiered gifts for new and returning participants.


Interested in participating?

Complete and submit this form, and a Pfizer New Haven Clinical Research Unit (PCRU) representative will contact you. Please note: volunteers completing this form must be able to read and speak English at an 8th grade level.

You may also call 1-800-254-6398 and speak with a PCRU representative to learn more.

For Japanese language assistance only, please call 1-833-711-9984. We apologize, our representatives cannot take calls in languages other than English or Japanese at this time.

The personal data gathered here will be collected, processed, and maintained in a confidential manner. Your information will be stored in our research unit’s database. We may use this information to invite you to participate in current and future clinical studies at the PCRU. You will have full access to your records at the Pfizer New Haven Clinical Research Unit and the opportunity to correct them if necessary.

All fields marked with * are required.