When it comes to your health, no one is a better advocate than you. That’s why it’s important that you understand your condition and available treatment options, including investigational medicines that are being studied in clinical trials, also called studies.
Explore our breast cancer clinical trials and see if one is right for you.
We are committed to supporting people living with breast cancer by developing innovative medicines, providing educational resources, and helping to remove barriers to care. We have several study medicines in development that may have the potential to help people with various types of breast cancer.
Together with the breast cancer community, we've made meaningful change for women and men living with breast cancer. But our work is far from finished. It is through the commitment of people like you that we can work to make progress against breast cancer. We understand how important a good support system is and are ready to walk alongside you every step of the way.
Participating in these studies
Every study has unique requirements that determine who can participate.
Our clinical trial finder, powered by Leal Health, is an online questionnaire that can help see if you may be eligible to participate in a breast cancer study based on your health and medical history. It also gives you access to a dedicated member of the Leal Health Patient Support team who can answer your questions, help guide you in discussing your options with your oncologist and connect you to a study team (physician and nurses) to learn more. All the information you provide will be kept confidential.
The clinical trial finder can see if you may be eligible to participate in a breast cancer study sponsored by Pfizer and other organizations to maximize your opportunities to participate. To view our studies in more detail, please refer to the tiles below.
Condition
Breast cancer
Age
18+ years
Sex
Female and Male
This information is a summary of the eligibility criteria across the studies in this program. Each study will have its own unique requirements for who may participate (eligibility criteria). To learn more about the requirements for a study that is actively recruiting, visit the study’s webpage below. Only the research study staff can determine if you qualify to enroll in the study.
Get started — See if you may qualify
A first step as you consider participating in these studies is to answer a 5-minute online questionnaire about your health and medical history. Please answer the questions to the best of your ability and to the extent you feel comfortable. You can skip questions, however, providing more information will help our clinical trial finder, a secure system powered by Leal Health, to see if you may be eligible for a study based on your health and medical history.
By entering your information into the online questionnaire, you are creating an account and profile with Leal Health which will allow you to see if you may be eligible for any breast cancer studies. At the end of the online questionnaire, you will be able to see how many studies you may potentially qualify for.
By providing your contact information, you are providing permission for a member of the Leal Health Patient Support Team to contact you and discuss next steps. They will be available to help you navigate the process of finding a study, answering your questions, and helping you prepare to talk with your oncologist.
If you would like to be referred to a nearby clinic, your Patient Support Team Member will ask you to provide written permission for Leal Health to share your contact information with the study team at the clinic who will then contact you and will likely ask you to come in for an appointment. Only the study team can determine if you meet all the study’s eligibility criteria and are able to enroll in the study.
If it appears that you may be eligible to participate in a Pfizer breast cancer study after completing the online questionnaire, you will see the list of potential Pfizer sponsored studies first. If there are no Pfizer sponsored studies in the list, you can provide permission for Leal Health to continue searching for an appropriate study sponsored by another organization.
We encourage you to review Leal Health’s privacy policy (linked below) before you complete the online questionnaire. Your answers including any personal information will be kept confidential by Leal Health throughout the prescreening process.
Your answers to the online questionnaire will only be linked to you if your responses indicate that you may be eligible to participate in a study and you choose to share your contact information with that study team. Pfizer study team members and our partners will have access to reports containing aggregated (combined) data that will not be directly linked back to you.
Pfizer Breast Cancer Clinical Trials
Understanding common eligibility criteria in breast cancer clinical trials
Every clinical trial has unique requirements for participation. These requirements are called eligibility criteria and may include things like the stage of your cancer, the type of breast cancer you have, and any treatment you received in the past.
When considering if a specific clinical trial is a good fit for you, a doctor evaluates:
- The stage of the breast cancer (1 through 4) at diagnosis, which tells them how big the tumor is and if the cancer has spread outside of the breast(s)
- The tumor grade score (1 to 3). Grade 1 cells look more like normal cells compared to Grade 3 cells
- Whether this is first-time cancer or cancer that has returned after prior therapy
- Your age, menopausal status, overall health, and treatment preferences
Other things a doctor may consider in evaluating whether a specific clinical trial is right for you:
- Hormone receptor status: Some breast cancer cells have estrogen and/or progesterone receptors on their surface and require the hormones estrogen and/or progesterone to grow. This is described as being hormone receptor-positive, or HR-positive breast cancer.
- Human epidermal growth factor receptor 2 (HER2) status: HER2 is another kind of receptor found on the surface of some breast cancer cells. When there are too many HER2 receptors, it is described as HER2-positive breast cancer and can lead to uncontrolled breast cell division and tumor formation.
- Triple-negative breast cancer (TNBC): Triple-negative breast cancer does not have any of the receptors commonly found in breast cancer, namely the receptors for estrogen, progesterone, or HER2.
Understanding common eligibility criteria in breast cancer clinical trials
Why participate in a clinical trial?
Why participate in a clinical trial?
Before you decide to participate in one of our studies, we will review the study details with you including what you can expect to happen during the study, the length of participation, and potential risks and benefits.
Your safety and privacy are the highest priority while participating in any of our studies.
- Your participation in our clinical trials is voluntary, and you are free to withdraw at any time, for any reason.
- Your decision to stop being in a clinical trial will not affect your regular medical care or any benefits that you are entitled to.
If a Pfizer breast cancer study is a good fit for you and you decide to take part, you will receive:
- Close monitoring of your breast cancer during the study
- Access to investigational medicines or standard of care treatment (which is the established treatment currently used in people with your breast cancer type)
- The study medicine and any study-related procedures provided at no cost (these are generally covered by the sponsor)
- Reimbursement for any reasonable expenses that you may have as a result of taking part in the study such as parking, meals, or other travel-related expenses (check with your study team as this may vary)
- The opportunity to help advance scientific knowledge of breast cancer and potentially help other people with breast cancer in the future
Representation is key
While the majority of people with breast cancer are women, about 1% are male. And although non-Hispanic whites have higher rates of breast cancer, African American and blacks die at higher rates from breast cancer.
Many factors controlled by genetics, including race, ethnicity, and gender, can impact how people respond to a medicine and/or vaccine. That is why it is so important that clinical trials include people of all backgrounds.
Choosing to participate is very personal and many factors may weigh in your decision-making. Historically, there have been unjust practices in clinical research and barriers to access that have stood in the way of inclusive participation. Today, many protections are in place to better protect participants’ rights and safety and ensure that clinical trials are conducted ethically.
If you choose to participate, you must provide your consent (permission) before joining a study and can decide to withdraw from the study at any time, for any reason.
Your participation in a clinical trial may help advance potential investigational medicines for people across the globe. When everyone is accurately represented, we can improve the development of novel study medicines, learn how they work for different people, and reduce health disparities among underrepresented populations.
Representation is key
Learn more about the clinical trial experience
Hear from the Women of When We Tri(al)
Black women make up 3% of clinical trial participants. Meet women both diagnosed with breast cancer and those who work in clinical trials as they talk about things to consider and their experiences in breast cancer clinical trials.
Karen’s Story
Karen, a stage 4 triple negative breast cancer survivor, shares her experience as a previous clinical trial participant.
Deltra’s Story
Deltra, as a metastatic breast cancer patient, talks about the importance of knowing your available treatment options.
Reducing Health Inequities for Black Women with Breast Cancer
People of color continue to be underrepresented in global clinical trials. Together, Pfizer, Inc. and the Tigerlily Foundation are helping to tackle barriers to equitable care for women of color and patient populations living with breast cancer.
Science Will Win: Clinical Trials: Bringing Research to Life
Adam Rutherford and guest break down the next steps in how potential breast cancer treatments move forward from the lab. What role do clinical trials play in the development of potential treatments? How are clinical trials developed? How can participants access clinical trials? And how are researchers and advocacy groups working to break down barriers in access to clinical trials?Science Will Win: Breast Cancer: The Science, the Challenges, the Solutions
Oncologists have more innovative methods for treating breast cancer than ever before. Adam Rutherford and guests explore the hurdles and successes researchers face as they work to develop potential targeted therapies for breast cancer.Frequently asked questions
Breast cancer is a type of cancer that starts in one or both breasts; cancer begins when cells start to grow out of control. Though it occurs mostly in women, men can get breast cancer. Each year about 2.3 million people are diagnosed with breast cancer globally.
Metastatic breast cancer—sometimes called advanced or Stage IV breast cancer—is breast cancer that has spread beyond the breast, most commonly to the lungs, bones, liver, and brain. It is the most advanced stage of breast cancer. Even though metastatic breast cancer is in another part of the body, it is still made up of breast cancer cells and is treated as breast cancer. There are a number of treatments and research options for people living with metastatic breast cancer.
The Pfizer breast cancer clinical trials are being conducted to see if study medicines may help stop or slow the spread of breast cancer.
Each clinical trial is unique and has different eligibility criteria (also called requirements) to participate. A trial may evaluate an investigational medicine for a specific type or stage of breast cancer or may be looking for people who have responded in a certain way to previous therapy. Once you’ve completed the online questionnaire and spoken to a member of the Patient Support Team, they can help determine if there is a study for you.
If you have spoken to a member of the Patient Support Team and are not eligible to participate in a Pfizer breast cancer study, you can provide permission for Leal Health to continue searching for a study sponsored by another organization. We also encourage you to check back on the website frequently as additional studies are starting on an ongoing basis.
The study medicine and any study-related procedures are provided at no cost (these are generally covered by the study sponsor). You may be reimbursed for any reasonable expenses that you may have as a result of taking part in a Pfizer breast cancer clinical trial. This may include parking, meals, or other travel-related expenses (check with the study team as this may vary).
Your privacy is the highest priority while participating in our clinical trials. The information you provide will not be shared with anyone who is not directly associated with the Pfizer breast cancer clinical trials without your permission.
