Clinical Trial for COVID-19. | Pfizer

The purpose of this study is to learn about the side effects (safety) of the study medicine PF-07321332 (nirmatrelvir)/ritonavir for the treatment of mild to moderate COVID-19 infection in adults with severe renal impairment. The study will also look at the amounts of study drug in your blood. There will be 24 participants in this study; 12 of them will have severe renal impairment and not be on hemodialysis and 12 of them will be on hemodialysis.

All participants in this study will take PF-07321332 (nirmatrelvir)/ritonavir by mouth for 5 days. During this time, they will have to collect blood samples to measure the study drug levels in their blood. After taking the study drug for 5 days, the participants will have follow-up visits for about another 28 days for a total of about 34 days in the study. The study team will check how each participant is doing during regular visits at the study clinic.

Closest Location

To find study locations, use the location search box below.

Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition

COVID-19

Sex

Male or Female

Age

18+ years

View more eligibility criteria on ClinicalTrials.gov

Study Locations

Location

Distance

Amicis Research Center - Granada Hills

Granada Hills, California, United States, 91344

Recruiting

Amicis Research Center

Granada Hills, California, United States, 91344

Recruiting

DaVita Inglewood Dialysis

Inglewood, California, United States, 90301

Recruiting

Northridge Kidney Center

Northridge, California, United States, 91324

Recruiting

Clinnova Research - Redondo Beach

Redondo Beach, California, United States, 90277

Recruiting

Santa Clarita Dialysis

Santa Clarita, California, United States, 91355

Recruiting

laurel Canyon Dialysis

Sun Valley, California, United States, 91352

Recruiting

Desert Cities Diaylsis

Victorville, California, United States, 92392

Recruiting

Desert Cities Dialysis - Hesperia

Victorville, California, United States, 92395

Recruiting

Fresenius Kidney Care Ft Lauderdale #2036

Fort Lauderdale, Florida, United States, 33312

Recruiting

South Florida Research Institute

Lauderdale Lakes, Florida, United States, 33313

Recruiting

Fresenius Kidney Care Florida Kidney Center #1095

Lauderhill, Florida, United States, 33319

Recruiting

GCP Research, Global Clinical professionals

Saint Petersburg, Florida, United States, 33705

Recruiting

Fresenius Kidney Care Tamarac-JV #6606

Tamarac, Florida, United States, 33321

Recruiting

Fresenius Kidney Care Hillsborough #100706

Tampa, Florida, United States, 33603

Recruiting

Genesis Clinical Research, LLC

Tampa, Florida, United States, 33603

Recruiting

Fresenius Kidney Care Tampa #1130

Tampa, Florida, United States, 33609

Recruiting

Fresenius Kidney Care Ybor City #1863

Tampa, Florida, United States, 33610

Recruiting

Fresenius Kidney Care Town and Country #100474

Tampa, Florida, United States, 33615

Recruiting

Fresenius Kidney Care Carrollwood #1805

Tampa, Florida, United States, 33624

Recruiting

Fresenius Kidney Care- Caldwell

Caldwell, Idaho, United States, 83605

Recruiting

Fresenius Kidney Care-Meridian

Meridian, Idaho, United States, 83642

Recruiting

Liberty Dialysis- Nampa

Nampa, Idaho, United States, 83686

Recruiting

Boise Kidney & Hypertension Institute

Nampa, Idaho, United States, 83687

Recruiting

Piedmont Dialysis Center

Winston-Salem, North Carolina, United States, 27101

Recruiting

Brookview Hills Research Associates

Winston-Salem, North Carolina, United States, 27103

Recruiting

Northside Dialysis Center

Winston-Salem, North Carolina, United States, 27105

Recruiting

Fresenius Kidney Care / Roane County #2829

Harriman, Tennessee, United States, 37748

Recruiting

Fresenius Kidney Care / Fort Sanders #1597

Knoxville, Tennessee, United States, 37921

Recruiting

Fresenius Kidney Care / Cedar Bluff #6942

Knoxville, Tennessee, United States, 37923

Recruiting

Knoxville Kidney Center, PLLC

Knoxville, Tennessee, United States, 37923

Recruiting

Arlington Nephrology

Arlington, Texas, United States, 76015

Recruiting

South Arlington Dialysis Center

Arlington, Texas, United States, 76015

Recruiting

Grand Prairie Dialysis Center

Grand Prairie, Texas, United States, 75051

Recruiting

University of Virginia Health System

Charlottesville, Virginia, United States, 22908

Recruiting

Swedish Covenant Hospital

Chicago, Illinois, United States, 60625

Not yet recruiting

NorthShore University HealthSystem - Evanston Hospital

Evanston, Illinois, United States, 60201

Not yet recruiting

DaVita Evanston Renal Center

Evanston, Illinois, United States, 60202

Not yet recruiting

DaVita Glen Dialysis

Glenview, Illinois, United States, 60026

Not yet recruiting

NorthShore University HealthSystem - Glenbrook Hospital

Glenview, Illinois, United States, 60026

Not yet recruiting

NorthShore University HealthSystem - Highland Park Hospital

Highland Park, Illinois, United States, 60035

Not yet recruiting

NorthShore University HealthSystem - Skokie Hospital

Skokie, Illinois, United States, 60076

Not yet recruiting

NorthShore Immediate Care Center - Skokie at Old Orchard Woods

Skokie, Illinois, United States, 60077

Not yet recruiting

NorthShore University HealthSystem - Clinical Trials Center

Skokie, Illinois, United States, 60077

Not yet recruiting