NCT04543188

Simple Title
A TWO-PART, PHASE 1A/B, OPEN-LABEL, MULTICENTER TRIAL EVALUATING PHARMACOKINETICS, SAFETY AND EFFICACY OF PF-07284890 (ARRY 461) IN PARTICIPANTS WITH BRAF V600 MUTANT SOLID TUMORS WITH AND WITHOUT BRAIN INVOLVEMENT

Malignant Melanoma

Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition

Malignant Melanoma, Carcinoma, Non-Small-Cell Lung, Brain Neoplasms, Primary, Brain Neoplasms, Malignant Neoplasms

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.
Sex
Male or Female
The sex of people who may participate in a clinical trial (all, female, male). Sex is a person’s classification based on assignment at birth. Eligibility based on sex is distinct from eligibility based on gender.
Age
16+ years
The age a person must be to participate in a clinical trial.
View more eligibility criteria on ClinicalTrials.gov

Study Locations

Study Locations
64 trials found.

City of Hope (City of Hope National Medical Center, City of Hope Medical Center)

Duarte, California, United States, 91010
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UNC Hospitals, The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27514
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Dana-Farber Cancer Institute - Chestnut Hill

Newton, Massachusetts, United States, 02459
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HealthPartners Cancer Center at Regions Hospital

Saint Paul, Minnesota, United States, 55101
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Regions Hospital Pharmacy

Saint Paul, Minnesota, United States, 55101
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City of Hope Investigational Drug Services (IDS)

Duarte, California, United States, 91010
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Memorial Sloan Kettering Cancer Center Rockefeller Outpatient Pavilion

New York, New York, United States, 10022
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Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065
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UNC Cancer Hospital Infusion Pharmacy

Chapel Hill, North Carolina, United States, 27514
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Duke Eye Center

Durham, North Carolina, United States, 27705
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Imaging: Brigham and Women's Ambulatory Care

Chestnut Hill, Massachusetts, United States, 02467
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Duke University Medical Center, Investigational Chemotherapy Services

Durham, North Carolina, United States, 27710
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Duke University Medical Center

Durham, North Carolina, United States, 27710
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Tennessee Oncology PLLC

Franklin, Tennessee, United States, 37067
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Sarah Cannon Research Institute - Pharmacy

Nashville, Tennessee, United States, 37203
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Tennessee Oncology PLLC

Nashville, Tennessee, United States, 37203
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The University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030
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Rambam Health Care Campus

Haifa, ?eif?, Israel, 3109601
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Rabin Medical Center

Petah-Tikva, Hamerkaz, Israel, 49100
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Imaging: Brigham and Women's Mass General Healthcare Center

Foxboro, Massachusetts, United States, 02035
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Hadassah Medical Center

Jerusalem, Yerushalayim, Israel, 9112001
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Imaging: Brigham and Women's Radiology, Coolidge Corner Imaging

Brookline, Massachusetts, United States, 02446
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Johns Hopkins University / Johns Hopkins Hospital

Baltimore, Maryland, United States, 21231
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University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States, 52242
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Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02215
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Northwestern Medical Group

Chicago, Illinois, United States, 60611
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Richard M Schulze Family Foundation Outpatient Center at McKinley Campus

Tampa, Florida, United States, 33612
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Moffitt Cancer Center

Tampa, Florida, United States, 33612
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Northwestern Memorial Hospital

Chicago, Illinois, United States, 60611
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Community Health Network, Inc.

Indianapolis, Indiana, United States, 46250
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UCSF Medical Center

San Francisco, California, United States, 94158
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UCSF Helen Diller Family Comprehensive Cancer Center

San Francisco, California, United States, 94143
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Massachusetts General Hospital

Boston, Massachusetts, United States, 02114
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Ophthalmic Consultants of Boston Inc (OCB)

Boston, Massachusetts, United States, 02114
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Brigham & Women's Hospital

Boston, Massachusetts, United States, 02115
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Imaging: Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115
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Jewish General Hospital

Montreal, Quebec, Canada, H3T 1E2
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Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada, M4N 3M5
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Hamilton Health Sciences-Juravinski Cancer Centre

Hamilton, Ontario, Canada, L8V5C2
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University of Wisconsin Hospitals and Clinics

Madison, Wisconsin, United States, 53792
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Orlando Health Cancer Institute

Orlando, Florida, United States, 32806
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Sheba Medical Center

Ramat Gan, Hamerkaz, Israel, 5262100
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Sourasky Medical Center

Tel Aviv, Tell Abīb, Israel, 6423906
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West Chester Hospital

West Chester, Ohio, United States, 45069
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University of Cincinnati Medical Center

Cincinnati, Ohio, United States, 45219
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Princess Margaret Cancer Centre

Toronto, Ontario, Canada, M5G 2M9
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The University of Kansas Clinical Research Center

Fairway, Kansas, United States, 66205
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Carl & Edyth Lindner Center for Research & Education at TCH and TCH Cancer Center

Cincinnati, Ohio, United States, 45219
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Siteman Cancer Center - South County

Saint Louis, Missouri, United States, 63129
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Michigan Health Professionals (PI Clinic)

Farmington Hills, Michigan, United States, 48334
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Revive Research Institute

Sterling Heights, Michigan, United States, 48314
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Siteman Cancer Center - West County

Creve Coeur, Missouri, United States, 63141
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Siteman Cancer Center - North County

Florissant, Missouri, United States, 63031
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Barnes-Jewish Hospital

Saint Louis, Missouri, United States, 63110
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Washington University School of Medicine

Saint Louis, Missouri, United States, 63110
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Siteman Cancer Center - St Peters

Saint Peters, Missouri, United States, 63376
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The University of Kansas Cancer Center - Investigational Drug Services

Fairway, Kansas, United States, 66205
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Laura and Isaac Perlmutter Cancer Center

New York, New York, United States, 10016
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NYU Langone Health

New York, New York, United States, 10016
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NYU Langone Medical Center (Tisch Hospital)

New York, New York, United States, 10016
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NYU Langone Radiology- ACC East 41st street

New York, New York, United States, 10017
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The University of Kansas Cancer Center

Westwood, Kansas, United States, 66205
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The University of Kansas Hospital

Kansas City, Kansas, United States, 66160
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Washington University Infusion Center Pharmacy

Saint Louis, Missouri, United States, 63110
Not yet recruiting Get directions