NCT03587116

Simple Title
AN OPEN-LABEL, NON-INVESTIGATIONAL PRODUCT, MULTI-CENTER, LEAD-IN STUDY TO EVALUATE PROSPECTIVE EFFICACY AND SAFETY DATA OF FACTOR IX OR FACTOR VIII PROPHYLAXIS REPLACEMENT THERAPY IN THE USUAL CARE SETTING OF MODERATELY SEVERE TO SEVERE ADULT HEMOPHILIA B SUBJECTS (FIX:C≤2%) WHO ARE NEGATIVE FOR NEUTRALIZING nAb TO AAV VECTOR SPARK100 AND MODERATELY SEVERE TO SEVERE HEMOPHILIA A ADULT SUBJECTS (FVIII:C≤1%) WHO ARE NEGATIVE FOR nAb TO AAV VECTOR SB-525 CAPSID (AAV6), PRIOR TO THE RESPECTIVE THERAPEUTIC PH 3 GENE THERAPY STUDIES (See Detailed Description Section for Official Protocol Title)

Hemophilia B

Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition

Hemophilia B, Hemophilia A

The disease, disorder, syndrome, illness, or injury that is being studied. On ClinicalTrials.gov, conditions may also include other health-related issues, such as lifespan, quality of life, and health risks.
Sex
Male
The sex of people who may participate in a clinical trial (all, female, male). Sex is a person’s classification based on assignment at birth. Eligibility based on sex is distinct from eligibility based on gender.
Age
18 - 64 years
The age a person must be to participate in a clinical trial.
View more eligibility criteria on ClinicalTrials.gov

Study Locations

Study Locations
59 trials found.

University of California, San Francisco - Outpatient Hematology Clinic

San Francisco, California, United States, 94143
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Skåne University Hospital

Malmö, Sweden, 205 02
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Nagoya University Hospital - Transfusion Medicine

Nagoya, Aichi, Japan, 466-8560
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Sapporo Tokushukai Hospital

Sapporo, Hokkaido, Japan, 004-0041
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Saitama Medical University Hospital

Iruma-gun, Saitama, Japan, 350-0495
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National Center for Child Health and Development

Setagaya-ku, Tokyo, Japan, 157-8535
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Kyungpook National University Hospital

Daegu, Korea, Republic of, 41944
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Kyung Hee University Hospital At Gangdong

Seoul, Korea, Republic of, 05278
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King Faisal Specialist Hospital & Research Center

Riyadh, Saudi Arabia
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Hospital Universitario Virgen de la Arrixaca

El Palmar, Murcia, Spain, 30120
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Hospital de la Santa Creu i Sant Pau

Barcelona, Spain, 08025
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Hospital Universitari Vall d´Hebrón

Barcelona, Spain, 08035
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H.U. Rio Hortega

Valladolid, Spain, 47012
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Changhua Christian Hospital

Changhua, Taiwan, 500
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Mississippi Center for Advanced Medicine

Madison, Mississippi, United States, 39110
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Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung, Taiwan, 807
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Chung Shan Medical University Hospital

Taichung City, Taiwan, 40201
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Taichung Veterans General Hospital

Taichung, Taiwan, 40705
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National Taiwan University Hospital

Taipei, Taiwan, 10002
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Ege Universitesi Tip Fakultesi Cocuk Sagligi Ve Hastaliklari Anabilim Dali Pediatric Hematoloji

Bornova, İ̇zmir, Turkey, 35040
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Acibadem Adana Hospital, Department of Pediatric Hematology

Adana, Turkey, 01130
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Gaziantep University Sahinbey Training and Research Hospital

Gaziantep, Turkey, 27310
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Istanbul University Oncology Institute

Istanbul, Turkey, 34093
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Newcastle upon Tyne Hospitals NHS Foundation Trust

Newcastle upon Tyne, Tyne & Wear, United Kingdom, NE1 4LP
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Non Malignant Haematology Research Unit

Newcastle upon Tyne, Tyne & Wear, United Kingdom, NE1 4LP
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Clinical Research Facility

Glasgow, United Kingdom, G31 2ER
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Department of Haematology

Glasgow, United Kingdom, G4 0SF
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Università degli studi di Roma "La Sapienza"- Policlinico Umberto I

Roma, Italy, 00161
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Azienda Ospedaliera Universitaria Federico II

Napoli, Italy, 80131
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SODc. Malattie Emorragiche e della Coagulazione Centro di Riferimento Regionale per le

Firenze, Italy, 50134
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McMaster University Medical Centre - Hamilton Health Sciences

Hamilton, Ontario, Canada, L8N 3Z5
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Penn Blood Disorder Center

Philadelphia, Pennsylvania, United States, 19104
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Penn Comprehensive Hemophilia & Thrombosis Program, Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104
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Royal Prince Alfred Hospital

Camperdown, New South Wales, Australia, 2050
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Royal Brisbane and Women's Hospital

Herston, Queensland, Australia, 4029
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Royal Adelaide Hospital

Adelaide, South Australia, Australia, 5000
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The Alfred Hospital

Melbourne, Victoria, Australia, 3004
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Fiona Stanley Hospital

Murdoch, Western Australia, Australia, 6150
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Cliniques universitaires Saint-Luc/Unité d'Hématology et Hémostase

Brussels, Belgium, 1200
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Centro de Hematologia e Hemoterapia - Hemocentro de Campinas - UNICAMP

Campinas, SAO Paulo, Brazil, 13083-878
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lnstituto Estadual de Hematologia Arthur de Siqueira Cavalcanti - HEMORIO

Rio de Janeiro, Brazil, 20211-030
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IRCCS - AOU di Bologna, Policlinico di Sant'Orsola

Bologna, BO, Italy, 40138
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Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo

São Paulo, Brazil, 05403-000
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St. Michael's Hospital

Toronto, Ontario, Canada, M5B 1W8
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CHRU de Brest - Hôpital Morvan

Brest, France, 29200
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Hôpital Cardiologique Louis Pradel

Bron, France, 69677
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Hopital Necker, Hematologie Adultes

Paris, France, 75015
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Vivantes Klinikum Friedrichshain

Berlin, Germany, 10249
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Universitatsklinikum Bonn. Anstalt des oeffentlichen Rechts

Bonn, Germany, 53127
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Universitaetsklinikum Giessen

Giessen, Germany, 35392
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Universität und Universitätsklinikum des Saarlandes

Homburg/Saar, Germany, 66421
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General Hospital of Athens "Hippokration"

Athens, Attica, Greece, 11527
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General Hospital of Athens "LAIKO", 2nd Regional Blood Transfusion Center

Athens, Attica, Greece, 11527
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Guy's and St Thomas' NHS Foundation Trust

London, United Kingdom, SE1 7EH
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Hospital Das Clínicas Da Faculdade de Medicina de Ribeirao Preto Da Universidade de Sao Paulo

Ribeirão Preto, SÃO Paulo, Brazil, 14051-140
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Taipei Medical University Hospital

Taipei City, Taiwan, 110
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Centro Estadual de Hemoterapia e Hematologia Marcos Daniel Santos - Hemoes

Vitoria, Espirito Santo, Brazil, 29047-105
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King Abdulaziz Medical City

Riyadh, Saudi Arabia, 11426
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Universitaetsklinikum Frankfurt, Goethe-Universitaet

Frankfurt/Main, Germany, 60590
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