Clinical Trial for Sickle Cell Disease. | Pfizer

This study consists of four parts, Parts A, B, C, and D.

Part A is a single dose pharmacokinetic (PK) study in pediatric participants with Sickle Cell Disease ages 6 to 17 years.
Part B is a multiple dose, safety, exploratory, efficacy, and PK study in adolescent participants with Sickle Cell Disease ages 12 to 17 years.
Part C is a multiple dose, safety, tolerability, and PK study, which includes the assessment of hematological effects and the effect on TCD flow velocity of voxelotor in pediatric participants with Sickle Cell Disease ages 4 to 17 years.
Part D is a multiple dose, safety, tolerability, and PK study, which examines the hematological effects of voxelotor in pediatric participants with Sickle Cell Disease ages 6 months to \< 4 years.

Closest Location

To find study locations, use the location search box below.

Who may participate

Each clinical study has its own guidelines for who may participate, called eligibility criteria. These factors can include your age, sex, overall health, type and stage of disease, and personal treatment history. However, only the research study staff can determine if you qualify to enroll in the study.

Condition

Sickle Cell Disease

Sex

Male or Female

Age

6 months - 17 years

View more eligibility criteria on ClinicalTrials.gov

Study Locations

Location

Distance

Brody School of Medicine at East Carolina University

Greenville, North Carolina, United States, 27834

Recruiting

ECU Physicians

Greenville, North Carolina, United States, 27834

Recruiting

St. Jude Children's Research Hospital - Pharmaceutical Services

Memphis, Tennessee, United States, 38105

Recruiting

American University of Beirut - Medical Center

Beirut, Lebanon

Recruiting

Nini Hospital

Tripoli, Lebanon

Recruiting

University College London Hospital, NHS Foundation Trust

London, Greater London, United Kingdom, NW1 2PG

Recruiting

Barts Health NHS Trust, The Royal London Hospital

London, United Kingdom, E1 1BB

Recruiting

Guy's and St Thoma's NHS Foundation Trust, Evelina London Children's Hospital

London, United Kingdom, SE1 7EH

Recruiting